ENSGALG00000003744


Gallus gallus

Features
Gene ID: ENSGALG00000003744
  
Biological name :ADAM19
  
Synonyms : ADAM19 / ADAM metallopeptidase domain 19
  
Possible biological names infered from orthology : Disintegrin and metalloproteinase domain-containing protein 19 / O35674 / Q9H013
  
Species: Gallus gallus
  
Chr. number: 13
Strand: 1
Band:
Gene start: 11323099
Gene end: 11349859
  
Corresponding Affymetrix probe sets: GgaAffx.2344.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005930
NCBI entrez gene - 416244     See in Manteia.
RefSeq - NM_001195122
RefSeq Peptide - NP_001182051
swissprot - E1AP05
Ensembl - ENSGALG00000003744
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adam19bENSDARG00000067545Danio rerio
 ADAM19ENSG00000135074Homo sapiens
 Adam19ENSMUSG00000011256Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADAM33 / disintegrin and metalloproteinase domain-containing protein 33 precursor / Q923W9* / Q9BZ11* / ADAM metallopeptidase domain 33* / Disintegrin and metalloproteinase domain-containi...ENSGALG0000003060244
ADAM12 / disintegrin and metalloproteinase domain-containing protein 12 isoform 2 precursor / O43184* / Q61824* / ADAM metallopeptidase domain 12* / Disintegrin and metalloproteinase domai...ENSGALG0000004125542
ADAM23 / disintegrin and metalloproteinase domain-containing protein 23 / O75077* / Q9R1V7* / ADAM metallopeptidase domain 23*ENSGALG0000000858224
ADAM11 / ADAM metallopeptidase domain 11 / O75078* / Q9R1V4* / Disintegrin and metalloproteinase domain-containing protein 11 *ENSGALG0000003567323
ADAM22 / ADAM metallopeptidase domain 22 / Q9P0K1* / Q9R1V6* / Disintegrin and metalloproteinase domain-containing protein 22 *ENSGALG0000000897623


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001590  Peptidase M12B, ADAM/reprolysin
 IPR001762  Disintegrin domain
 IPR002870  Peptidase M12B, propeptide
 IPR006586  ADAM, cysteine-rich
 IPR013032  EGF-like, conserved site
 IPR018358  Disintegrin, conserved site
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR033596  ADAM19 peptidase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006509 membrane protein ectodomain proteolysis IEA
 biological_processGO:0007507 heart development IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Invadopodia formation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008293 SH3PXD2A / SH3 and PX domains 2A / O89032* / Q5TCZ1* / SH3 and PX domain-containing protein 2A *  / complex / reaction






 

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