ENSGALG00000008293


Gallus gallus

Features
Gene ID: ENSGALG00000008293
  
Biological name :SH3PXD2A
  
Synonyms : SH3 and PX domains 2A / SH3PXD2A
  
Possible biological names infered from orthology : O89032 / Q5TCZ1 / SH3 and PX domain-containing protein 2A
  
Species: Gallus gallus
  
Chr. number: 6
Strand: -1
Band:
Gene start: 23812676
Gene end: 24036604
  
Corresponding Affymetrix probe sets: Gga.12548.1.S1_s_at (Chicken Array)   Gga.12548.3.S1_s_at (Chicken Array)   Gga.15165.1.S1_at (Chicken Array)   Gga.15872.1.S1_s_at (Chicken Array)   GgaAffx.22520.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000013488
NCBI entrez gene - 423876     See in Manteia.
RefSeq - XM_004942262
RefSeq - XM_015288722
RefSeq - XM_421741
swissprot - E1C207
Ensembl - ENSGALG00000008293
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sh3pxd2aaENSDARG00000060148Danio rerio
 sh3pxd2abENSDARG00000061758Danio rerio
 Q5TCZ1ENSG00000107957Homo sapiens
 O89032ENSMUSG00000053617Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SH3PXD2B / SH3 and PX domains 2B / A1X283* / A2AAY5* / SH3 and PX domain-containing protein 2B *ENSGALG0000000283133
NCF1 / neutrophil cytosol factor 1 / P14598* / Q09014* / neutrophil cytosolic factor 1*ENSGALG0000000118911
NOXO1 / NADPH oxidase organizer 1 / Q8NFA2* / Q8VCM2*ENSGALG000000055729


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR001683  Phox homologous domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006801 superoxide metabolic process IEA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0055114 oxidation-reduction process IBA
 biological_processGO:0071800 podosome assembly IBA
 biological_processGO:0072593 reactive oxygen species metabolic process IEA
 biological_processGO:0072675 osteoclast fusion IEA
 cellular_componentGO:0002102 podosome IEA
 molecular_functionGO:0016176 superoxide-generating NADPH oxidase activator activity IBA
 molecular_functionGO:0035091 phosphatidylinositol binding IBA


Pathways (from Reactome)
Pathway description
Invadopodia formation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000041255 ADAM12 / disintegrin and metalloproteinase domain-containing protein 12 isoform 2 precursor / O43184* / Q61824* / ADAM metallopeptidase domain 12* / Disintegrin and metalloproteinase domai...  / reaction / complex
 ENSGALG00000003744 ADAM19 / ADAM metallopeptidase domain 19 / O35674* / Q9H013* / Disintegrin and metalloproteinase domain-containing protein 19 *  / complex / reaction






 

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