ENSDARG00000067545


Danio rerio

Features
Gene ID: ENSDARG00000067545
  
Biological name :adam19b
  
Synonyms : adam19b / ADAM metallopeptidase domain 19b
  
Possible biological names infered from orthology : ADAM19 / ADAM metallopeptidase domain 19 / Disintegrin and metalloproteinase domain-containing protein 19 / O35674 / Q9H013
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 6546516
Gene end: 6614102
  
Corresponding Affymetrix probe sets: Dr.25856.1.S1_at (Zebrafish Array)   XM_694823_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000087985
Ensembl peptide - ENSDARP00000114607
NCBI entrez gene - 571252     See in Manteia.
RefSeq - XM_694823
swissprot - F1Q4N9
swissprot - F1QK73
ZFIN ID - ZDB-GENE-070705-541
Ensembl - ENSDARG00000067545
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ADAM19ENSGALG00000003744Gallus gallus
 ADAM19ENSG00000135074Homo sapiens
 Adam19ENSMUSG00000011256Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
adam12 / ADAM metallopeptidase domain 12 / O43184* / Q61824* / Disintegrin and metalloproteinase domain-containing protein 12 *ENSDARG0000007906837
adam15 / ADAM metallopeptidase domain 15 / O88839* / Q13444* / Disintegrin and metalloproteinase domain-containing protein 15 *ENSDARG0000008921334
adam19a / ADAM metallopeptidase domain 19a / ADAM33* / Q9BZ11* / ADAM metallopeptidase domain 33*ENSDARG0000005969329
ADAM12 (1 of many) / ADAM metallopeptidase domain 12 / ADAM12* / O43184*ENSDARG0000011606229
adam8a / ADAM metallopeptidase domain 8a / ADAM8* / Q05910* / P78325* / ADAM metallopeptidase domain 8* / Disintegrin and metalloproteinase domain-containing protein 8 *ENSDARG0000000145227
adam28 / ADAM metallopeptidase domain 28 / ADAM7* / Q9UKQ2* / O35227* / Q9H2U9* / Q9JLN6* / ADAM metallopeptidase domain 7* / Disintegrin and metalloproteinase domain-containing protein 7 *...ENSDARG0000003551426
adam8b / ADAM metallopeptidase domain 8b / ADAM8* / Q05910* / P78325* / ADAM metallopeptidase domain 8* / Disintegrin and metalloproteinase domain-containing protein 8 *ENSDARG0000005764426
adam22 / ADAM metallopeptidase domain 22 / Q9P0K1* / Q9R1V6* / Disintegrin and metalloproteinase domain-containing protein 22 *ENSDARG0000006053225
adam11 / ADAM metallopeptidase domain 11 / O75078* / Q9R1V4* / Disintegrin and metalloproteinase domain-containing protein 11 *ENSDARG0000007920424
adam23a / ADAM metallopeptidase domain 23a / ADAM23* / O75077* / Q9R1V7* / ADAM metallopeptidase domain 23* / Disintegrin and metalloproteinase domain-containing protein 23 *ENSDARG0000006232323
FO818722.1 / ADAM23* / O75077* / ADAM metallopeptidase domain 23*ENSDARG0000011245321


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001590  Peptidase M12B, ADAM/reprolysin
 IPR001762  Disintegrin domain
 IPR002870  Peptidase M12B, propeptide
 IPR006586  ADAM, cysteine-rich
 IPR013032  EGF-like, conserved site
 IPR018358  Disintegrin, conserved site
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR033596  ADAM19 peptidase
 IPR034027  Reprolysin domain, adamalysin-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006509 membrane protein ectodomain proteolysis IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Invadopodia formation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000060148 sh3pxd2aa / SH3 and PX domains 2Aa / Q5TCZ1* / O89032* / SH3PXD2A* / SH3 and PX domains 2A* / SH3 and PX domain-containing protein 2A *  / reaction / complex
 ENSDARG00000061758 sh3pxd2ab / SH3 and PX domains 2Ab / Q5TCZ1* / O89032* / SH3PXD2A* / SH3 and PX domains 2A* / SH3 and PX domain-containing protein 2A *  / complex / reaction






 

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