ENSDARG00000057644


Danio rerio

Features
Gene ID: ENSDARG00000057644
  
Biological name :adam8b
  
Synonyms : adam8b / ADAM metallopeptidase domain 8b
  
Possible biological names infered from orthology : ADAM8 / ADAM metallopeptidase domain 8 / Disintegrin and metalloproteinase domain-containing protein 8 / P78325 / Q05910
  
Species: Danio rerio
  
Chr. number: 12
Strand: -1
Band:
Gene start: 9096963
Gene end: 9132682
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000066470
Ensembl peptide - ENSDARP00000124311
NCBI entrez gene - 100005593     See in Manteia.
swissprot - E7F6J8
swissprot - F8W3Y8
ZFIN ID - ZDB-GENE-070808-1
Ensembl - ENSDARG00000057644
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ADAM8ENSG00000151651Homo sapiens
 Adam8ENSMUSG00000025473Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
adam8a / ADAM metallopeptidase domain 8a / ADAM8* / Q05910* / P78325* / ADAM metallopeptidase domain 8* / Disintegrin and metalloproteinase domain-containing protein 8 *ENSDARG0000000145247
adam28 / ADAM metallopeptidase domain 28 / ADAM7* / Q9UKQ2* / O35227* / Q9H2U9* / Q9JLN6* / ADAM metallopeptidase domain 7* / Disintegrin and metalloproteinase domain-containing protein 7 *...ENSDARG0000003551434
adam12 / ADAM metallopeptidase domain 12 / O43184* / Q61824* / Disintegrin and metalloproteinase domain-containing protein 12 *ENSDARG0000007906832
adam15 / ADAM metallopeptidase domain 15 / O88839* / Q13444* / Disintegrin and metalloproteinase domain-containing protein 15 *ENSDARG0000008921332
adam19b / ADAM metallopeptidase domain 19b / ADAM19* / O35674* / Q9H013* / ADAM metallopeptidase domain 19* / Disintegrin and metalloproteinase domain-containing protein 19 *ENSDARG0000006754530
ADAM12 (1 of many) / ADAM metallopeptidase domain 12 / ADAM12* / O43184*ENSDARG0000011606226
adam22 / ADAM metallopeptidase domain 22 / Q9P0K1* / Q9R1V6* / Disintegrin and metalloproteinase domain-containing protein 22 *ENSDARG0000006053224
adam11 / ADAM metallopeptidase domain 11 / O75078* / Q9R1V4* / Disintegrin and metalloproteinase domain-containing protein 11 *ENSDARG0000007920424
adam23a / ADAM metallopeptidase domain 23a / ADAM23* / O75077* / Q9R1V7* / ADAM metallopeptidase domain 23* / Disintegrin and metalloproteinase domain-containing protein 23 *ENSDARG0000006232322
FO818722.1 / ADAM23* / O75077* / ADAM metallopeptidase domain 23*ENSDARG0000011245321
adam19a / ADAM metallopeptidase domain 19a / ADAM33* / Q9BZ11* / ADAM metallopeptidase domain 33*ENSDARG0000005969321


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001590  Peptidase M12B, ADAM/reprolysin
 IPR001762  Disintegrin domain
 IPR002870  Peptidase M12B, propeptide
 IPR006586  ADAM, cysteine-rich
 IPR013032  EGF-like, conserved site
 IPR018358  Disintegrin, conserved site
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR034027  Reprolysin domain, adamalysin-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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