ENSDARG00000060532


Danio rerio

Features
Gene ID: ENSDARG00000060532
  
Biological name :adam22
  
Synonyms : adam22 / ADAM metallopeptidase domain 22
  
Possible biological names infered from orthology : Disintegrin and metalloproteinase domain-containing protein 22 / Q9P0K1 / Q9R1V6
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 43152727
Gene end: 43284939
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000127768
Ensembl peptide - ENSDARP00000154749
Ensembl peptide - ENSDARP00000111920
NCBI entrez gene - 100126805     See in Manteia.
swissprot - A7YYF5
swissprot - F1QF43
swissprot - X1WC25
ZFIN ID - ZDB-GENE-070810-1
Ensembl - ENSDARG00000060532
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ADAM22ENSGALG00000008976Gallus gallus
 ADAM22ENSG00000008277Homo sapiens
 Adam22ENSMUSG00000040537Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
adam11 / ADAM metallopeptidase domain 11 / O75078* / Q9R1V4* / Disintegrin and metalloproteinase domain-containing protein 11 *ENSDARG0000007920442
adam23a / ADAM metallopeptidase domain 23a / ADAM23* / O75077* / Q9R1V7* / ADAM metallopeptidase domain 23* / Disintegrin and metalloproteinase domain-containing protein 23 *ENSDARG0000006232338
FO818722.1 / ADAM23* / O75077* / ADAM metallopeptidase domain 23*ENSDARG0000011245335
adam12 / ADAM metallopeptidase domain 12 / O43184* / Q61824* / Disintegrin and metalloproteinase domain-containing protein 12 *ENSDARG0000007906825
adam19b / ADAM metallopeptidase domain 19b / ADAM19* / O35674* / Q9H013* / ADAM metallopeptidase domain 19* / Disintegrin and metalloproteinase domain-containing protein 19 *ENSDARG0000006754525
adam15 / ADAM metallopeptidase domain 15 / O88839* / Q13444* / Disintegrin and metalloproteinase domain-containing protein 15 *ENSDARG0000008921325
adam8a / ADAM metallopeptidase domain 8a / ADAM8* / Q05910* / P78325* / ADAM metallopeptidase domain 8* / Disintegrin and metalloproteinase domain-containing protein 8 *ENSDARG0000000145223
adam8b / ADAM metallopeptidase domain 8b / ADAM8* / Q05910* / P78325* / ADAM metallopeptidase domain 8* / Disintegrin and metalloproteinase domain-containing protein 8 *ENSDARG0000005764422
adam28 / ADAM metallopeptidase domain 28 / ADAM7* / Q9UKQ2* / O35227* / Q9H2U9* / Q9JLN6* / ADAM metallopeptidase domain 7* / Disintegrin and metalloproteinase domain-containing protein 7 *...ENSDARG0000003551422
ADAM12 (1 of many) / ADAM metallopeptidase domain 12 / ADAM12* / O43184*ENSDARG0000011606218
adam19a / ADAM metallopeptidase domain 19a / ADAM33* / Q9BZ11* / ADAM metallopeptidase domain 33*ENSDARG0000005969317


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001590  Peptidase M12B, ADAM/reprolysin
 IPR001762  Disintegrin domain
 IPR002870  Peptidase M12B, propeptide
 IPR006586  ADAM, cysteine-rich
 IPR013032  EGF-like, conserved site
 IPR018358  Disintegrin, conserved site
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR034027  Reprolysin domain, adamalysin-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA


Pathways (from Reactome)
Pathway description
LGI-ADAM interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000020493 lgi1a / leucine-rich, glioma inactivated 1a / LGI4* / Q8N135* / leucine rich repeat LGI family member 4*  / complex / reaction
 ENSDARG00000032565 cacng2a / calcium channel, voltage-dependent, gamma subunit 2a / CACNG2* / O88602* / Q9Y698* / Voltage-dependent calcium channel gamma-2 subunit * / calcium voltage-gated channel auxiliary ...  / complex
 ENSDARG00000058421 lgi1b / leucine-rich, glioma inactivated 1b / LGI4* / Q8K1S1* / Q8N135* / leucine rich repeat LGI family member 4*  / complex / reaction
 ENSDARG00000041358 lgi3 / leucine-rich repeat LGI family, member 3 / Q8K406* / Q8N145*  / reaction / complex
 ENSDARG00000070626 cacng8b / calcium channel, voltage-dependent, gamma subunit 8b / CACNG8* / Q8WXS5* / voltage-dependent calcium channel gamma-8 subunit * / calcium voltage-gated channel auxiliary subunit gamma 8*  / complex
 ENSDARG00000074669 cacng4b / calcium channel, voltage-dependent, gamma subunit 4b / CACNG4* / Q9UBN1* / calcium voltage-gated channel auxiliary subunit gamma 4*  / complex
 ENSDARG00000076401 cacng3b / calcium channel, voltage-dependent, gamma subunit 3b / CACNG3* / O60359* / Q9JJV5* / Voltage-dependent calcium channel gamma-3 subunit * / calcium voltage-gated channel auxiliary ...  / complex
 ENSDARG00000020450 cacng8a / calcium channel, voltage-dependent, gamma subunit 8a / CACNG8* / Q8WXS5* / voltage-dependent calcium channel gamma-8 subunit * / calcium voltage-gated channel auxiliary subunit gamma 8*  / complex






 

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