ENSDARG00000079068


Danio rerio

Features
Gene ID: ENSDARG00000079068
  
Biological name :adam12
  
Synonyms : adam12 / ADAM metallopeptidase domain 12
  
Possible biological names infered from orthology : Disintegrin and metalloproteinase domain-containing protein 12 / O43184 / Q61824
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 32158951
Gene end: 32334107
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000099354
Ensembl peptide - ENSDARP00000135966
Ensembl peptide - ENSDARP00000129618
NCBI entrez gene - 563275     See in Manteia.
swissprot - E7FEZ4
swissprot - A0A0R4INJ8
swissprot - X1WHA6
ZFIN ID - ZDB-GENE-070809-1
Ensembl - ENSDARG00000079068
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ADAM12ENSGALG00000041255Gallus gallus
 ADAM12ENSG00000148848Homo sapiens
 Adam12ENSMUSG00000054555Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADAM12 (1 of many) / ADAM metallopeptidase domain 12 / ADAM12* / O43184*ENSDARG0000011606246
adam19b / ADAM metallopeptidase domain 19b / ADAM19* / O35674* / Q9H013* / ADAM metallopeptidase domain 19* / Disintegrin and metalloproteinase domain-containing protein 19 *ENSDARG0000006754536
adam15 / ADAM metallopeptidase domain 15 / O88839* / Q13444* / Disintegrin and metalloproteinase domain-containing protein 15 *ENSDARG0000008921334
adam8a / ADAM metallopeptidase domain 8a / ADAM8* / Q05910* / P78325* / ADAM metallopeptidase domain 8* / Disintegrin and metalloproteinase domain-containing protein 8 *ENSDARG0000000145228
adam8b / ADAM metallopeptidase domain 8b / ADAM8* / Q05910* / P78325* / ADAM metallopeptidase domain 8* / Disintegrin and metalloproteinase domain-containing protein 8 *ENSDARG0000005764428
adam19a / ADAM metallopeptidase domain 19a / ADAM33* / Q9BZ11* / ADAM metallopeptidase domain 33*ENSDARG0000005969327
adam28 / ADAM metallopeptidase domain 28 / ADAM7* / Q9UKQ2* / O35227* / Q9H2U9* / Q9JLN6* / ADAM metallopeptidase domain 7* / Disintegrin and metalloproteinase domain-containing protein 7 *...ENSDARG0000003551426
adam22 / ADAM metallopeptidase domain 22 / Q9P0K1* / Q9R1V6* / Disintegrin and metalloproteinase domain-containing protein 22 *ENSDARG0000006053225
adam11 / ADAM metallopeptidase domain 11 / O75078* / Q9R1V4* / Disintegrin and metalloproteinase domain-containing protein 11 *ENSDARG0000007920424
adam23a / ADAM metallopeptidase domain 23a / ADAM23* / O75077* / Q9R1V7* / ADAM metallopeptidase domain 23* / Disintegrin and metalloproteinase domain-containing protein 23 *ENSDARG0000006232322
FO818722.1 / ADAM23* / O75077* / ADAM metallopeptidase domain 23*ENSDARG0000011245321


Protein motifs (from Interpro)
Interpro ID Name
 IPR001590  Peptidase M12B, ADAM/reprolysin
 IPR001762  Disintegrin domain
 IPR002870  Peptidase M12B, propeptide
 IPR006586  ADAM, cysteine-rich
 IPR018358  Disintegrin, conserved site
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR034027  Reprolysin domain, adamalysin-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Invadopodia formation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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