ENSDARG00000032565


Danio rerio

Features
Gene ID: ENSDARG00000032565
  
Biological name :cacng2a
  
Synonyms : cacng2a / calcium channel, voltage-dependent, gamma subunit 2a
  
Possible biological names infered from orthology : CACNG2 / calcium voltage-gated channel auxiliary subunit gamma 2 / O88602 / Q9Y698 / Voltage-dependent calcium channel gamma-2 subunit
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 29714775
Gene end: 29845175
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000041387
NCBI entrez gene - 393614     See in Manteia.
RefSeq - NM_200641
RefSeq Peptide - NP_956935
swissprot - Q6PFS3
ZFIN ID - ZDB-GENE-040426-1401
Ensembl - ENSDARG00000032565
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CACNG2ENSGALG00000031977Gallus gallus
 CACNG2ENSG00000166862Homo sapiens
 Cacng2ENSMUSG00000019146Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cacng3b / calcium channel, voltage-dependent, gamma subunit 3b / CACNG3* / O60359* / Q9JJV5* / Voltage-dependent calcium channel gamma-3 subunit * / calcium voltage-gated channel auxiliary ...ENSDARG0000007640173
cacng8b / calcium channel, voltage-dependent, gamma subunit 8b / CACNG8* / Q8WXS5* / voltage-dependent calcium channel gamma-8 subunit * / calcium voltage-gated channel auxiliary subunit gamma 8*ENSDARG0000007062660
cacng4b / calcium channel, voltage-dependent, gamma subunit 4b / CACNG4* / Q9UBN1* / calcium voltage-gated channel auxiliary subunit gamma 4*ENSDARG0000007466960
cacng8a / calcium channel, voltage-dependent, gamma subunit 8a / CACNG8* / Q8WXS5* / voltage-dependent calcium channel gamma-8 subunit * / calcium voltage-gated channel auxiliary subunit gamma 8*ENSDARG0000002045059
cacng3a / calcium channel, voltage-dependent, gamma subunit 3a / CACNG3* / O60359* / Q9JJV5* / Voltage-dependent calcium channel gamma-3 subunit * / calcium voltage-gated channel auxiliary ...ENSDARG0000005846059
cacng4a / calcium channel, voltage-dependent, gamma subunit 4a / CACNG4* / Q9UBN1* / calcium voltage-gated channel auxiliary subunit gamma 4*ENSDARG0000011554052
cacng5a / calcium channel, voltage-dependent, gamma subunit 5a / CACNG5* / Q9UF02* / calcium voltage-gated channel auxiliary subunit gamma 5*ENSDARG0000000332626
cacng7a / calcium channel, voltage-dependent, gamma subunit 7a / CACNG7* / P62955* / P62956* / Voltage-dependent calcium channel gamma-7 subunit * / calcium voltage-gated channel auxiliary ...ENSDARG0000006300626
cacng7b / calcium channel, voltage-dependent, gamma subunit 7b / CACNG7* / P62955* / P62956* / Voltage-dependent calcium channel gamma-7 subunit * / calcium voltage-gated channel auxiliary ...ENSDARG0000007062426
cacng5a / cacng5b / calcium channel, voltage-dependent, gamma subunit 5b / CACNG5* / Q9UF02* / Q8VHW4* / Voltage-dependent calcium channel gamma-5 subunit * / calcium voltage-gated channel ...ENSDARG0000003924025


Protein motifs (from Interpro)
Interpro ID Name
 IPR004031  PMP-22/EMP/MP20/Claudin superfamily
 IPR005422  Voltage-dependent calcium channel, gamma-2 subunit
 IPR008368  Voltage-dependent calcium channel, gamma subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0019226 transmission of nerve impulse IBA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0070588 calcium ion transmembrane transport IBA
 biological_processGO:0098990 AMPA selective glutamate receptor signaling pathway IMP
 biological_processGO:2000311 regulation of AMPA receptor activity IBA
 cellular_componentGO:0005891 voltage-gated calcium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032281 AMPA glutamate receptor complex IBA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005245 voltage-gated calcium channel activity IBA
 molecular_functionGO:0005262 calcium channel activity IEA
 molecular_functionGO:0016247 channel regulator activity IBA


Pathways (from Reactome)
Pathway description
Presynaptic depolarization and calcium channel opening
Phase 0 - rapid depolarisation
Phase 2 - plateau phase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain decreased amount , abnormal
hindbrain AMPA glutamate receptor clustering decreased occurrence , abnormal
Show

 ZFA:0000114 heart heart edematous , abnormal
Show

 ZFA:0009149 Mauthner neuron Mauthner neuron has fewer parts of type Mauthner neuron AMPA glutamate receptor complex, abnormal
Mauthner neuron AMPA selective glutamate receptor signaling pathway decreased rate , abnormal
Mauthner neuron AMPA selective glutamate receptor signaling pathway decreased magnitude , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000060532 adam22 / ADAM metallopeptidase domain 22 / Q9P0K1* / Q9R1V6* / Disintegrin and metalloproteinase domain-containing protein 22 *  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr