ENSGALG00000008701


Gallus gallus

Features
Gene ID: ENSGALG00000008701
  
Biological name :XDH
  
Synonyms : xanthine dehydrogenase/oxidase / XDH
  
Possible biological names infered from orthology : P47989 / Q00519 / xanthine dehydrogenase
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 4482183
Gene end: 4522989
  
Corresponding Affymetrix probe sets: Gga.16188.1.S1_at (Chicken Array)   Gga.2494.1.S1_at (Chicken Array)   Gga.2494.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000014144
NCBI entrez gene - 396025     See in Manteia.
RefSeq - NM_205127
RefSeq - XM_015283349
RefSeq Peptide - NP_990458
swissprot - F1NIY2
Ensembl - ENSGALG00000008701
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 xdhENSDARG00000055240Danio rerio
 XDHENSG00000158125Homo sapiens
 XdhENSMUSG00000024066Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AOX1 / aldehyde oxidase ENSGALG0000000818553
AOX2 / aldehyde oxidase 2 / Aox4* / Aox3* / G3X982* / Q3TYQ9* / Q5SGK3* / Aldehyde oxidase 4 * / Aldehyde oxidase 3 *ENSGALG0000002087651


Protein motifs (from Interpro)
Interpro ID Name
 IPR000674  Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead
 IPR001041  2Fe-2S ferredoxin-type iron-sulfur binding domain
 IPR002346  Molybdopterin dehydrogenase, FAD-binding
 IPR002888  [2Fe-2S]-binding
 IPR005107  CO dehydrogenase flavoprotein, C-terminal
 IPR006058  2Fe-2S ferredoxin, iron-sulphur binding site
 IPR008274  Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding
 IPR012675  Beta-grasp domain superfamily
 IPR014307  Xanthine dehydrogenase, small subunit
 IPR014309  Xanthine dehydrogenase, molybdopterin binding subunit
 IPR016166  FAD-binding, type 2
 IPR016167  FAD-binding, type 2, subdomain 1
 IPR016208  Aldehyde oxidase/xanthine dehydrogenase
 IPR022407  Oxidoreductase, molybdopterin binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001933 negative regulation of protein phosphorylation IEA
 biological_processGO:0001937 negative regulation of endothelial cell proliferation IEA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0007595 lactation IEA
 biological_processGO:0009115 xanthine catabolic process IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0030856 regulation of epithelial cell differentiation IEA
 biological_processGO:0045602 negative regulation of endothelial cell differentiation IEA
 biological_processGO:0051898 negative regulation of protein kinase B signaling IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:1900745 positive regulation of p38MAPK cascade IEA
 biological_processGO:1900747 negative regulation of vascular endothelial growth factor signaling pathway IEA
 biological_processGO:2000379 positive regulation of reactive oxygen species metabolic process IEA
 biological_processGO:2001213 negative regulation of vasculogenesis IEA
 cellular_componentGO:0016529 sarcoplasmic reticulum IEA
 molecular_functionGO:0004854 xanthine dehydrogenase activity IEA
 molecular_functionGO:0004855 xanthine oxidase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0009055 electron transfer activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEA
 molecular_functionGO:0030151 molybdenum ion binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043546 molybdopterin cofactor binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051537 2 iron, 2 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Purine catabolism
Butyrophilin (BTN) family interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr