ENSDARG00000055240


Danio rerio

Features
Gene ID: ENSDARG00000055240
  
Biological name :xdh
  
Synonyms : xanthine dehydrogenase / xdh
  
Possible biological names infered from orthology : P47989 / Q00519
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 33340675
Gene end: 33374538
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000072020
Ensembl peptide - ENSDARP00000147093
NCBI entrez gene - 560486     See in Manteia.
RefSeq - XM_683891
swissprot - E7F022
ZFIN ID - ZDB-GENE-070719-9
Ensembl - ENSDARG00000055240
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 XDHENSGALG00000008701Gallus gallus
 XDHENSG00000158125Homo sapiens
 XdhENSMUSG00000024066Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
aox6 / aldehyde oxidase 6 / Aox2* / Aox4* / Aox3* / AOX1* / Q5SGK3* / G3X982* / Q06278* / Q3TYQ9* / aldehyde oxidase 1* / Aldehyde oxidase 4 * / Aldehyde oxidase 3 * / Aldehyde oxidase 2 *ENSDARG0000002005451
aox5 / aldehyde oxidase 5ENSDARG0000007147550


Protein motifs (from Interpro)
Interpro ID Name
 IPR000674  Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead
 IPR001041  2Fe-2S ferredoxin-type iron-sulfur binding domain
 IPR002346  Molybdopterin dehydrogenase, FAD-binding
 IPR002888  [2Fe-2S]-binding
 IPR005107  CO dehydrogenase flavoprotein, C-terminal
 IPR006058  2Fe-2S ferredoxin, iron-sulphur binding site
 IPR008274  Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding
 IPR012675  Beta-grasp domain superfamily
 IPR014307  Xanthine dehydrogenase, small subunit
 IPR014309  Xanthine dehydrogenase, molybdopterin binding subunit
 IPR016166  FAD-binding, type 2
 IPR016167  FAD-binding, type 2, subdomain 1
 IPR016208  Aldehyde oxidase/xanthine dehydrogenase
 IPR022407  Oxidoreductase, molybdopterin binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009115 xanthine catabolic process IBA
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004854 xanthine dehydrogenase activity IBA
 molecular_functionGO:0004855 xanthine oxidase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0009055 electron transfer activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEA
 molecular_functionGO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors IBA
 molecular_functionGO:0030151 molybdenum ion binding IEA
 molecular_functionGO:0043546 molybdopterin cofactor binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IBA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051537 2 iron, 2 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Purine catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000055240 xdh / xanthine dehydrogenase / P47989* / Q00519*  / complex






 

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