ENSGALG00000008909


Gallus gallus

Features
Gene ID: ENSGALG00000008909
  
Biological name :USP13
  
Synonyms : ubiquitin carboxyl-terminal hydrolase 13 / USP13
  
Possible biological names infered from orthology : Q5BKP2 / Q92995 / ubiquitin specific peptidase 13 / ubiquitin specific peptidase 13 (isopeptidase T-3)
  
Species: Gallus gallus
  
Chr. number: 9
Strand: -1
Band:
Gene start: 17437022
Gene end: 17477511
  
Corresponding Affymetrix probe sets: GgaAffx.5610.4.S1_at (Chicken Array)   GgaAffx.5610.4.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000014471
NCBI entrez gene - 429286     See in Manteia.
RefSeq - NM_001305103
RefSeq Peptide - NP_001292032
swissprot - A0A1I7Q407
Ensembl - ENSGALG00000008909
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 usp13ENSDARG00000079198Danio rerio
 USP13ENSG00000058056Homo sapiens
 Usp13ENSMUSG00000056900Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
USP5 / ubiquitin specific peptidase 5 / P45974* / P56399* / ubiquitin specific peptidase 5 (isopeptidase T)*ENSGALG0000001452558


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR001607  Zinc finger, UBP-type
 IPR009060  UBA-like superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR015940  Ubiquitin-associated domain
 IPR016652  Ubiquitinyl hydrolase
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0010506 regulation of autophagy IEA
 biological_processGO:0016579 protein deubiquitination IEA
 biological_processGO:0035523 protein K29-linked deubiquitination IEA
 biological_processGO:0044313 protein K6-linked deubiquitination IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0070536 protein K63-linked deubiquitination IEA
 biological_processGO:1904294 positive regulation of ERAD pathway IEA
 biological_processGO:1904378 maintenance of unfolded protein involved in ERAD pathway IEA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IEA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA
 molecular_functionGO:0043130 ubiquitin binding IEA
 molecular_functionGO:0044389 ubiquitin-like protein ligase binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051087 chaperone binding IEA
 molecular_functionGO:0070628 proteasome binding IEA
 molecular_functionGO:1904288 BAT3 complex binding IEA
 molecular_functionGO:1904454 ubiquitin-specific protease activity involved in positive regulation of ERAD pathway IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases
Regulation of PTEN stability and activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000010395 SIAH2 / siah E3 ubiquitin protein ligase 2 / O43255* / Q06986*  / complex / reaction






 

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