ENSGALG00000009287


Gallus gallus

Features
Gene ID: ENSGALG00000009287
  
Biological name :ATF2
  
Synonyms : ATF2 / cyclic AMP-dependent transcription factor ATF-2
  
Possible biological names infered from orthology : activating transcription factor 2 / P15336 / P16951
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 16722225
Gene end: 16768556
  
Corresponding Affymetrix probe sets: Gga.17372.1.S1_s_at (Chicken Array)   GgaAffx.22660.1.S1_at (Chicken Array)   GgaAffx.22660.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047984
Ensembl peptide - ENSGALP00000032623
NCBI entrez gene - 395727     See in Manteia.
RefSeq - NM_204904
RefSeq Peptide - NP_990235
swissprot - G1K360
swissprot - A0A1D5P5L3
Ensembl - ENSGALG00000009287
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atf2ENSDARG00000023903Danio rerio
 ATF2ENSG00000115966Homo sapiens
 Atf2ENSMUSG00000027104Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CREB5 / cAMP responsive element binding protein 5 / Q02930*ENSGALG0000003826546
ATF7* / Q8R0S1* / P17544* / Gm28047* / AC023509.3* / activating transcription factor 7* / Cyclic AMP-dependent transcription factor ATF-7 *ENSGALG0000003913435


Protein motifs (from Interpro)
Interpro ID Name
 IPR004827  Basic-leucine zipper domain
 IPR013087  Zinc finger C2H2-type
 IPR016378  Transcription factor cyclic AMP-dependent, CRE-BP1-type
 IPR029836  cAMP-dependent transcription factor ATF-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003151 outflow tract morphogenesis IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006970 response to osmotic stress IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0016573 histone acetylation IEA
 biological_processGO:0031573 intra-S DNA damage checkpoint IEA
 biological_processGO:0032915 positive regulation of transforming growth factor beta2 production IEA
 biological_processGO:0045444 fat cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0060612 adipose tissue development IEA
 biological_processGO:0110024 positive regulation of cardiac muscle myoblast proliferation IEA
 biological_processGO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0035861 site of double-strand break IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001102 RNA polymerase II activating transcription factor binding IEA
 molecular_functionGO:0001158 enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0004402 histone acetyltransferase activity IEA
 molecular_functionGO:0008140 cAMP response element binding protein binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0035497 cAMP response element binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
HATs acetylate histones
Activation of the AP-1 family of transcription factors
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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