ENSGALG00000009309


Gallus gallus

Features
Gene ID: ENSGALG00000009309
  
Biological name :EIF5A2
  
Synonyms : EIF5A2 / Eukaryotic translation initiation factor 5A-2 / Q07460
  
Possible biological names infered from orthology : Q8BGY2 / Q9GZV4
  
Species: Gallus gallus
  
Chr. number: 9
Strand: 1
Band:
Gene start: 19797645
Gene end: 19802487
  
Corresponding Affymetrix probe sets: Gga.18258.1.S1_at (Chicken Array)   Gga.18258.1.S1_s_at (Chicken Array)   Gga.4176.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000038570
Ensembl peptide - ENSGALP00000064802
Ensembl peptide - ENSGALP00000064161
Ensembl peptide - ENSGALP00000061927
NCBI entrez gene - 396545     See in Manteia.
RefSeq - NM_205532
RefSeq - XM_015291651
RefSeq Peptide - NP_990863
swissprot - A0A1B1XXT0
swissprot - A0A1L1S0Z7
swissprot - Q07460
swissprot - A0A1B1XXT1
Ensembl - ENSGALG00000009309
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif5aENSDARG00000017235Danio rerio
 EIF5A2ENSG00000163577Homo sapiens
 Eif5a2ENSMUSG00000050192Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001884  Translation elongation factor IF5A-like
 IPR008991  Translation protein SH3-like domain superfamily
 IPR012340  Nucleic acid-binding, OB-fold
 IPR014722  Ribosomal protein L2, domain 2
 IPR019769  Translation elongation factor, IF5A, hypusine site
 IPR020189  Translation elongation factor, IF5A C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0006414 translational elongation IEA
 biological_processGO:0006452 translational frameshifting IEA
 biological_processGO:0008284 positive regulation of cell proliferation ISS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0045901 positive regulation of translational elongation IEA
 biological_processGO:0045905 positive regulation of translational termination IEA
 biological_processGO:0051028 mRNA transport IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005643 nuclear pore IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003743 translation initiation factor activity IEA
 molecular_functionGO:0003746 translation elongation factor activity IEA
 molecular_functionGO:0043022 ribosome binding IEA


Pathways (from Reactome)
Pathway description
Hypusine synthesis from eIF5A-lysine


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000017524 DOHH / Q5ZIP3 / Deoxyhypusine hydroxylase / Q9BU89* / Q99LN9* / Gm48551* / predicted gene, 48551*  / reaction






 

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