ENSDARG00000017235


Danio rerio

Features
Gene ID: ENSDARG00000017235
  
Biological name :eif5a
  
Synonyms : eif5a / eukaryotic translation initiation factor 5A
  
Possible biological names infered from orthology : EIF5A2 / EIF5AL1 / Eukaryotic translation initiation factor 5A-1 / eukaryotic translation initiation factor 5A2 / eukaryotic translation initiation factor 5A-like 1 / P63241 / P63242 / Q6IS14 / Q8BGY2 / Q9GZV4
  
Species: Danio rerio
  
Chr. number: 24
Strand: -1
Band:
Gene start: 26481300
Gene end: 26485345
  
Corresponding Affymetrix probe sets: Dr.20010.3.S1_at (Zebrafish Array)   Dr.20010.3.S2_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000117595
Ensembl peptide - ENSDARP00000118000
Ensembl peptide - ENSDARP00000027654
Ensembl peptide - ENSDARP00000099088
Ensembl peptide - ENSDARP00000112654
Ensembl peptide - ENSDARP00000114277
NCBI entrez gene - 406464     See in Manteia.
swissprot - E9QD54
swissprot - Q6NX89
ZFIN ID - ZDB-GENE-040426-2229
Ensembl - ENSDARG00000017235
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EIF5A2ENSGALG00000009309Gallus gallus
 EIF5AENSG00000132507Homo sapiens
 EIF5A2ENSG00000163577Homo sapiens
 Q6IS14ENSG00000253626Homo sapiens
 Eif5aENSMUSG00000078812Mus musculus
 Eif5a2ENSMUSG00000050192Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
eif5a / eif5a2 / eukaryotic translation initiation factor 5A2ENSDARG0000005618679


Protein motifs (from Interpro)
Interpro ID Name
 IPR001884  Translation elongation factor IF5A-like
 IPR008991  Translation protein SH3-like domain superfamily
 IPR012340  Nucleic acid-binding, OB-fold
 IPR014722  Ribosomal protein L2, domain 2
 IPR019769  Translation elongation factor, IF5A, hypusine site
 IPR020189  Translation elongation factor, IF5A C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0006452 translational frameshifting IEA
 biological_processGO:0045901 positive regulation of translational elongation IEA
 biological_processGO:0045905 positive regulation of translational termination IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003743 translation initiation factor activity IEA
 molecular_functionGO:0003746 translation elongation factor activity IEA
 molecular_functionGO:0043022 ribosome binding IEA


Pathways (from Reactome)
Pathway description
Hypusine synthesis from eIF5A-lysine


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003564 dohh / deoxyhypusine hydroxylase/monooxygenase / Q99LN9* / Q9BU89* / Gm48551* / predicted gene, 48551* / deoxyhypusine hydroxylase*  / reaction
 ENSDARG00000003270 dhps / deoxyhypusine synthase / P49366* / Q3TXU5*  / reaction






 

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