ENSG00000253626


Homo sapiens

Features
Gene ID: ENSG00000253626
  
Biological name :EIF5AL1
  
Synonyms : EIF5AL1 / eukaryotic translation initiation factor 5A-like 1 / Q6IS14
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q22.3
Gene start: 79512601
Gene end: 79516440
  
Corresponding Affymetrix probe sets: 201122_x_at (Human Genome U133 Plus 2.0 Array)   201123_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000430706
NCBI entrez gene - 143244     See in Manteia.
RefSeq - NM_001099692
RefSeq Peptide - NP_001093162
swissprot - Q6IS14
Ensembl - ENSG00000253626
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif5aENSDARG00000017235Danio rerio
 Eif5aENSMUSG00000078812Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EIF5A / P63241 / eukaryotic translation initiation factor 5AENSG0000013250798
EIF5A2 / Q9GZV4 / eukaryotic translation initiation factor 5A2ENSG0000016357780


Protein motifs (from Interpro)
Interpro ID Name
 IPR001884  Translation elongation factor IF5A-like
 IPR008991  Translation protein SH3-like domain superfamily
 IPR012340  Nucleic acid-binding, OB-fold
 IPR014722  Ribosomal protein L2, domain 2
 IPR019769  Translation elongation factor, IF5A, hypusine site
 IPR020189  Translation elongation factor, IF5A C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006414 translational elongation IEA
 biological_processGO:0006452 translational frameshifting IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0045901 positive regulation of translational elongation IEA
 biological_processGO:0045905 positive regulation of translational termination IEA
 biological_processGO:0051028 mRNA transport IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005643 nuclear pore IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003746 translation elongation factor activity IEA
 molecular_functionGO:0043022 ribosome binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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