ENSDARG00000003270


Danio rerio

Features
Gene ID: ENSDARG00000003270
  
Biological name :dhps
  
Synonyms : deoxyhypusine synthase / dhps
  
Possible biological names infered from orthology : P49366 / Q3TXU5
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 13423935
Gene end: 13437817
  
Corresponding Affymetrix probe sets: Dr.11628.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000146348
Ensembl peptide - ENSDARP00000068557
Ensembl peptide - ENSDARP00000110283
NCBI entrez gene - 406329     See in Manteia.
swissprot - F1QVG4
swissprot - Q6NYK1
ZFIN ID - ZDB-GENE-040426-2001
Ensembl - ENSDARG00000003270
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DHPSENSG00000095059Homo sapiens
 DhpsENSMUSG00000060038Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002773  Deoxyhypusine synthase
 IPR029035  DHS-like NAD/FAD-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003323 type B pancreatic cell development IMP
 biological_processGO:0008612 peptidyl-lysine modification to peptidyl-hypusine IEA
 biological_processGO:0031017 exocrine pancreas development IMP
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0034038 deoxyhypusine synthase activity IBA


Pathways (from Reactome)
Pathway description
Hypusine synthesis from eIF5A-lysine


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000140 pancreas pancreas decreased amount , abnormal
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 ZFA:0001249 exocrine pancreas exocrine pancreas decreased length , abnormal
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 ZFA:0001260 endocrine pancreas endocrine pancreas decreased amount , abnormal
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 ZFA:0001369 anterior pancreatic bud anterior pancreatic bud type B pancreatic cell differentiation disrupted , abnormal
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 ZFA:0005754 primary islet primary islet has fewer parts of type pancreatic B cell , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000017235 eif5a / eukaryotic translation initiation factor 5A / Q9GZV4* / EIF5A2* / P63241* / P63242* / Q6IS14* / Q8BGY2* / EIF5AL1* / eukaryotic translation initiation factor 5A2* / Eukaryotic trans...  / reaction
 ENSDARG00000003270 dhps / deoxyhypusine synthase / P49366* / Q3TXU5*  / complex






 

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contact: otassy@igbmc.fr