ENSGALG00000009598


Gallus gallus

Features
Gene ID: ENSGALG00000009598
  
Biological name :EPRS
  
Synonyms : bifunctional glutamate/proline--tRNA ligase / EPRS
  
Possible biological names infered from orthology : glutamyl-prolyl-tRNA synthetase / Mus musculus glutamyl-prolyl-tRNA synthetase (Eprs), transcript variant 2, mRNA. / P07814 / Q8CGC7
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 18846482
Gene end: 18883499
  
Corresponding Affymetrix probe sets: Gga.8167.1.S1_s_at (Chicken Array)   GgaAffx.12651.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000015623
NCBI entrez gene - 421348     See in Manteia.
RefSeq - XM_015283651
RefSeq - NM_001006398
RefSeq - XM_015283649
RefSeq - XM_015283650
RefSeq Peptide - NP_001006398
swissprot - F1P179
Ensembl - ENSGALG00000009598
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eprsENSDARG00000060494Danio rerio
 EPRSENSG00000136628Homo sapiens
 EprsENSMUSG00000026615Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000738  WHEP-TRS domain
 IPR000924  Glutamyl/glutaminyl-tRNA synthetase
 IPR001412  Aminoacyl-tRNA synthetase, class I, conserved site
 IPR002314  Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)
 IPR004154  Anticodon-binding
 IPR004499  Proline-tRNA ligase, class IIa, archaeal-type
 IPR004526  Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic
 IPR006195  Aminoacyl-tRNA synthetase, class II
 IPR009068  S15/NS1, RNA-binding
 IPR010987  Glutathione S-transferase, C-terminal-like
 IPR011035  Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily
 IPR014729  Rossmann-like alpha/beta/alpha sandwich fold
 IPR016061  Proline-tRNA ligase, class II, C-terminal
 IPR017449  Prolyl-tRNA synthetase, class II
 IPR020056  Ribosomal protein L25/Gln-tRNA synthetase, N-terminal
 IPR020058  Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain
 IPR020059  Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain
 IPR020061  Glutamine-tRNA ligase, alpha-bundle domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006418 tRNA aminoacylation for protein translation IEA
 biological_processGO:0006424 glutamyl-tRNA aminoacylation IBA
 biological_processGO:0006433 prolyl-tRNA aminoacylation IBA
 biological_processGO:0017148 negative regulation of translation IEA
 biological_processGO:0043039 tRNA aminoacylation IEA
 biological_processGO:0071346 cellular response to interferon-gamma IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0017101 aminoacyl-tRNA synthetase multienzyme complex IEA
 cellular_componentGO:0097452 GAIT complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004812 aminoacyl-tRNA ligase activity IEA
 molecular_functionGO:0004818 glutamate-tRNA ligase activity IBA
 molecular_functionGO:0004827 proline-tRNA ligase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0035613 RNA stem-loop binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0051020 GTPase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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