ENSGALG00000010039


Gallus gallus

Features
Gene ID: ENSGALG00000010039
  
Biological name :BRE
  
Synonyms : BRE / BRISC and BRCA1-A complex member 2 / Q5ZML0
  
Possible biological names infered from orthology : BABAM2 / Q8K3W0 / Q9NXR7
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 27486112
Gene end: 27649822
  
Corresponding Affymetrix probe sets: Gga.9237.1.S1_at (Chicken Array)   Gga.9237.1.S1_s_at (Chicken Array)   GgaAffx.11477.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000016287
Ensembl peptide - ENSGALP00000059613
Ensembl peptide - ENSGALP00000049963
NCBI entrez gene - 421417     See in Manteia.
RefSeq - XM_015283708
RefSeq - XM_015283709
RefSeq - NM_001008458
RefSeq Peptide - NP_001008458
swissprot - Q5ZML0
swissprot - A0A1L1RLJ0
swissprot - A0A1D5PB43
Ensembl - ENSGALG00000010039
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 babam2ENSDARG00000038863Danio rerio
 BABAM2ENSG00000158019Homo sapiens
 Babam2ENSMUSG00000052139Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR010358  BRCA1-A complex subunit BRE


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006302 double-strand break repair IEA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0010212 response to ionizing radiation IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045739 positive regulation of DNA repair IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0072425 signal transduction involved in G2 DNA damage checkpoint IEA
 cellular_componentGO:0000152 nuclear ubiquitin ligase complex IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0070531 BRCA1-A complex IEA
 cellular_componentGO:0070552 BRISC complex IEA
 molecular_functionGO:0005164 tumor necrosis factor receptor binding IEA
 molecular_functionGO:0031593 polyubiquitin modification-dependent protein binding IEA


Pathways (from Reactome)
Pathway description
Metalloprotease DUBs
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
G2/M DNA damage checkpoint


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000005383 BRCC3 / BRCA1/BRCA2-containing complex subunit 3 / P46737* / Q7M757* / Gm5136* / P46736* / predicted gene 5136* / Lys-63-specific deubiquitinase BRCC36 *  / complex
 ENSGALG00000038054 FAM175B / BRISC complex subunit Abro1 / Q15018* / ABRAXAS2* / BRISC complex subunit* / abraxas 2, BRISC complex subunit*  / complex






 

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