ENSGALG00000010997


Gallus gallus

Features
Gene ID: ENSGALG00000010997
  
Biological name :DFNA5
  
Synonyms : DFNA5 / non-syndromic hearing impairment protein 5
  
Possible biological names infered from orthology : gasdermin E / Gasdermin-E Gasdermin-E, N-terminal Gasdermin-E, C-terminal / GSDME / O60443 / Q9Z2D3
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 31663719
Gene end: 31688494
  
Corresponding Affymetrix probe sets: Gga.6342.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000017887
NCBI entrez gene - 420623     See in Manteia.
RefSeq - XM_015281449
RefSeq - NM_001006361
RefSeq - XM_015281447
RefSeq - XM_015281448
RefSeq - XM_015281445
RefSeq - XM_015281446
RefSeq Peptide - NP_001006361
swissprot - F1NP12
Ensembl - ENSGALG00000010997
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gsdmeaENSDARG00000086762Danio rerio
 gsdmebENSDARG00000040485Danio rerio
 GSDMEENSG00000105928Homo sapiens
 GsdmeENSMUSG00000029821Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PJVK / pejvakin / Q0ZLH2* / Q0ZLH3*ENSGALG0000002343918


Protein motifs (from Interpro)
Interpro ID Name
 IPR007677  Gasdermin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008219 cell death IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IEA
 biological_processGO:0060113 inner ear receptor cell differentiation IEA
 biological_processGO:0070265 necrotic cell death IEA
 biological_processGO:0070269 pyroptosis IEA
 biological_processGO:0071356 cellular response to tumor necrosis factor IEA
 biological_processGO:0098586 cellular response to virus IEA
 biological_processGO:2001244 positive regulation of intrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IEA
 molecular_functionGO:1901612 cardiolipin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr