ENSGALG00000011387


Gallus gallus

Features
Gene ID: ENSGALG00000011387
  
Biological name :POLR2B
  
Synonyms : DNA-directed RNA polymerase II subunit RPB2 / POLR2B
  
Possible biological names infered from orthology : P30876 / Q8CFI7 / RNA polymerase II subunit B
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 49502216
Gene end: 49521628
  
Corresponding Affymetrix probe sets: Gga.9356.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000037170
NCBI entrez gene - 422621     See in Manteia.
RefSeq - NM_001006448
RefSeq Peptide - NP_001006448
swissprot - F1NCB0
Ensembl - ENSGALG00000011387
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P30876ENSG00000047315Homo sapiens
 Polr2bENSMUSG00000029250Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
POLR3B / Gallus gallus RNA polymerase III subunit B (POLR3B), mRNA. / P59470* / Q9NW08* / RNA polymerase III subunit B* / DNA-directed RNA polymerase III subunit RPC2 *ENSGALG0000001265538


Protein motifs (from Interpro)
Interpro ID Name
 IPR007120  DNA-directed RNA polymerase, subunit 2, hybrid-binding domain
 IPR007121  RNA polymerase, beta subunit, conserved site
 IPR007641  RNA polymerase Rpb2, domain 7
 IPR007642  RNA polymerase Rpb2, domain 2
 IPR007644  RNA polymerase, beta subunit, protrusion
 IPR007645  RNA polymerase Rpb2, domain 3
 IPR007646  RNA polymerase Rpb2, domain 4
 IPR007647  RNA polymerase Rpb2, domain 5
 IPR014724  RNA polymerase Rpb2, OB-fold
 IPR015712  DNA-directed RNA polymerase, subunit 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005665 DNA-directed RNA polymerase II, core complex IEA
 molecular_functionGO:0001055 RNA polymerase II activity IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA
 molecular_functionGO:0032549 ribonucleoside binding IEA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Transcriptional regulation by small RNAs
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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