ENSMUSG00000029250


Mus musculus

Features
Gene ID: ENSMUSG00000029250
  
Biological name :Polr2b
  
Synonyms : DNA-directed RNA polymerase II subunit RPB2 / Polr2b / Q8CFI7
  
Possible biological names infered from orthology : P30876 / RNA polymerase II subunit B
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: C3.3
Gene start: 77310147
Gene end: 77349324
  
Corresponding Affymetrix probe sets: 10522716 (MoGene1.0st)   1433552_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031167
NCBI entrez gene - 231329     See in Manteia.
MGI - MGI:2388280
RefSeq - NM_153798
RefSeq Peptide - NP_722493
swissprot - Q8CFI7
Ensembl - ENSMUSG00000029250
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 POLR2BENSGALG00000011387Gallus gallus
 P30876ENSG00000047315Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P59470 / Polr3b / DNA-directed RNA polymerase III subunit RPC2 / Q9NW08* / RNA polymerase III subunit B*ENSMUSG0000003445338


Protein motifs (from Interpro)
Interpro ID Name
 IPR007120  DNA-directed RNA polymerase, subunit 2, hybrid-binding domain
 IPR007121  RNA polymerase, beta subunit, conserved site
 IPR007641  RNA polymerase Rpb2, domain 7
 IPR007642  RNA polymerase Rpb2, domain 2
 IPR007644  RNA polymerase, beta subunit, protrusion
 IPR007645  RNA polymerase Rpb2, domain 3
 IPR007646  RNA polymerase Rpb2, domain 4
 IPR007647  RNA polymerase Rpb2, domain 5
 IPR015712  DNA-directed RNA polymerase, subunit 2
 IPR037033  DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily
 IPR037034  RNA polymerase Rpb2, domain 2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005665 DNA-directed RNA polymerase II, core complex IEA
 molecular_functionGO:0001055 RNA polymerase II activity IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA
 molecular_functionGO:0032549 ribonucleoside binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Transcriptional regulation by small RNAs
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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