ENSMUSG00000034453


Mus musculus

Features
Gene ID: ENSMUSG00000034453
  
Biological name :Polr3b
  
Synonyms : DNA-directed RNA polymerase III subunit RPC2 / P59470 / Polr3b
  
Possible biological names infered from orthology : Q9NW08 / RNA polymerase III subunit B
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: C1
Gene start: 84622292
Gene end: 84727178
  
Corresponding Affymetrix probe sets: 10365355 (MoGene1.0st)   1443466_s_at (Mouse Genome 430 2.0 Array)   1443494_at (Mouse Genome 430 2.0 Array)   1452949_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000149862
Ensembl peptide - ENSMUSP00000076418
NCBI entrez gene - 70428     See in Manteia.
MGI - MGI:1917678
RefSeq - NM_027423
RefSeq Peptide - NP_081699
swissprot - A0A1L1SSC8
swissprot - P59470
Ensembl - ENSMUSG00000034453
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 polr3bENSDARG00000062915Danio rerio
 POLR3BENSGALG00000012655Gallus gallus
 POLR3BENSG00000013503Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Polr2b / Q8CFI7 / DNA-directed RNA polymerase II subunit RPB2 / P30876* / RNA polymerase II subunit B*ENSMUSG0000002925039


Protein motifs (from Interpro)
Interpro ID Name
 IPR007120  DNA-directed RNA polymerase, subunit 2, hybrid-binding domain
 IPR007121  RNA polymerase, beta subunit, conserved site
 IPR007641  RNA polymerase Rpb2, domain 7
 IPR007642  RNA polymerase Rpb2, domain 2
 IPR007644  RNA polymerase, beta subunit, protrusion
 IPR007645  RNA polymerase Rpb2, domain 3
 IPR007646  RNA polymerase Rpb2, domain 4
 IPR007647  RNA polymerase Rpb2, domain 5
 IPR015712  DNA-directed RNA polymerase, subunit 2
 IPR037033  DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily
 IPR037034  RNA polymerase Rpb2, domain 2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006383 transcription by RNA polymerase III IEA
 biological_processGO:0032728 positive regulation of interferon-beta production IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045089 positive regulation of innate immune response IEA
 biological_processGO:0051607 defense response to virus IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005666 DNA-directed RNA polymerase III complex IEA
 molecular_functionGO:0001056 RNA polymerase III activity IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA
 molecular_functionGO:0032549 ribonucleoside binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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