ENSDARG00000062915


Danio rerio

Features
Gene ID: ENSDARG00000062915
  
Biological name :polr3b
  
Synonyms : polr3b / polymerase (RNA) III (DNA directed) polypeptide B
  
Possible biological names infered from orthology : DNA-directed RNA polymerase III subunit RPC2 / P59470 / Q9NW08 / RNA polymerase III subunit B
  
Species: Danio rerio
  
Chr. number: 18
Strand: -1
Band:
Gene start: 15382029
Gene end: 15420168
  
Corresponding Affymetrix probe sets: Dr.5471.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000085899
NCBI entrez gene - 562329     See in Manteia.
swissprot - F1QQA2
ZFIN ID - ZDB-GENE-030131-2887
Ensembl - ENSDARG00000062915
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 POLR3BENSGALG00000012655Gallus gallus
 POLR3BENSG00000013503Homo sapiens
 P59470ENSMUSG00000034453Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
polr2b / polymerase (RNA) II (DNA directed) polypeptide BENSDARG0000009878310


Protein motifs (from Interpro)
Interpro ID Name
 IPR007120  DNA-directed RNA polymerase, subunit 2, hybrid-binding domain
 IPR007121  RNA polymerase, beta subunit, conserved site
 IPR007641  RNA polymerase Rpb2, domain 7
 IPR007642  RNA polymerase Rpb2, domain 2
 IPR007644  RNA polymerase, beta subunit, protrusion
 IPR007645  RNA polymerase Rpb2, domain 3
 IPR007646  RNA polymerase Rpb2, domain 4
 IPR007647  RNA polymerase Rpb2, domain 5
 IPR015712  DNA-directed RNA polymerase, subunit 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006383 transcription by RNA polymerase III IEA
 biological_processGO:0009304 tRNA transcription IMP
 biological_processGO:0031017 exocrine pancreas development IMP
 biological_processGO:0048565 digestive tract development IMP
 cellular_componentGO:0005666 DNA-directed RNA polymerase III complex IBA
 molecular_functionGO:0001056 RNA polymerase III activity IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA
 molecular_functionGO:0032549 ribonucleoside binding IEA


Pathways (from Reactome)
Pathway description
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000123 liver liver decreased size , abnormal
Show

 ZFA:0000152 retina retina decreased size , abnormal
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 ZFA:0001155 enteric nervous system enteric nervous system complexity , abnormal
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 ZFA:0001249 exocrine pancreas exocrine pancreas aplastic , abnormal
exocrine pancreas decreased size , abnormal
exocrine pancreas quality , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch decreased size , abnormal
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 ZFA:0001338 intestine intestine decreased thickness , abnormal
intestine surface feature shape , abnormal
intestine smooth muscle contractile fiber organization quality , abnormal
intestine decreased size , abnormal
Show

 ZFA:0001439 anatomical system anatomical system quality , abnormal
Show

 ZFA:0001613 pharyngeal arch 3-7 pharyngeal arch 3-7 decreased size , abnormal
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 ZFA:0005124 intestinal epithelium intestinal epithelium anterior region has fewer parts of type epithelial cell microvillus, abnormal
intestinal epithelium epithelial cell cuboid , abnormal
intestinal epithelium degenerate , abnormal
intestinal epithelium positional polarity , abnormal
intestinal epithelium undifferentiated , abnormal
intestinal epithelium flat , abnormal
intestinal epithelium decreased size , abnormal
intestinal epithelium decreased thickness , abnormal
intestinal epithelium microvillus decreased size , abnormal
Show

 ZFA:0009092 exocrine cell exocrine cell undifferentiated , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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