ENSGALG00000011838


Gallus gallus

Features
Gene ID: ENSGALG00000011838
  
Biological name :GUCY2C
  
Synonyms : guanylate cyclase 2C / GUCY2C
  
Possible biological names infered from orthology : Heat-stable enterotoxin receptor / P25092 / Q3UWA6
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 48969433
Gene end: 49014451
  
Corresponding Affymetrix probe sets: GgaAffx.7522.1.S1_at (Chicken Array)   GgaAffx.7522.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000019294
Ensembl peptide - ENSGALP00000052444
NCBI entrez gene - 417968     See in Manteia.
RefSeq - XM_416207
swissprot - A0A1D5PI12
swissprot - E1BZE2
Ensembl - ENSGALG00000011838
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gucy2cENSDARG00000014320Danio rerio
 si:ch73-139e5.4ENSDARG00000056045Danio rerio
 GUCY2CENSG00000070019Homo sapiens
 Gucy2cENSMUSG00000042638Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GUCY2F* / P51841* / P52785* / Q02846* / Q5SDA5* / GUCY2D* / Gucy2e* / Guanylyl cyclase GC-E * / Retinal guanylyl cyclase 2 * / guanylate cyclase 2F, retinal* / guanylate cyclase 2D, retinal*ENSGALG0000000080830
NPR2 / natriuretic peptide receptor 2 / P20594* / Q6VVW5*ENSGALG0000002763029
ENSGALG0000003786924
ENSGALG0000001575321
Gucy1b2*ENSGALG0000000507615
GUCY1A2 / guanylate cyclase 1 soluble subunit alpha 2 / P33402*ENSGALG0000001717314
ENSGALG0000004301413
GUCY1B1 / guanylate cyclase 1 soluble subunit beta 1 / O54865* / Q02153* / guanylate cyclase 1, soluble, beta 1*ENSGALG0000000936113
GUCY1A1 / guanylate cyclase 1 soluble subunit alpha 1 / Q02108* / Q9ERL9* / guanylate cyclase 1, soluble, alpha 1*ENSGALG0000003594613


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001054  Adenylyl cyclase class-3/4/guanylyl cyclase
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001828  Receptor, ligand binding region
 IPR011009  Protein kinase-like domain superfamily
 IPR018297  Adenylyl cyclase class-4/guanylyl cyclase, conserved site
 IPR028082  Periplasmic binding protein-like I
 IPR029787  Nucleotide cyclase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006182 cGMP biosynthetic process IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0009190 cyclic nucleotide biosynthetic process IEA
 biological_processGO:0009636 response to toxic substance IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0008074 guanylate cyclase complex, soluble IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004383 guanylate cyclase activity IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016849 phosphorus-oxygen lyase activity IEA


Pathways (from Reactome)
Pathway description
Digestion


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000027269 GUCA2A / P33680* / Q02747* / Guanylin * / guanylate cyclase activator 2A*  / reaction / complex
 ENSGALG00000011838 GUCY2C / guanylate cyclase 2C / P25092* / Q3UWA6* / Heat-stable enterotoxin receptor *  / complex






 

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