ENSGALG00000027630


Gallus gallus

Features
Gene ID: ENSGALG00000027630
  
Biological name :NPR2
  
Synonyms : natriuretic peptide receptor 2 / NPR2
  
Possible biological names infered from orthology : P20594 / Q6VVW5
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 9095088
Gene end: 9106955
  
Corresponding Affymetrix probe sets: GgaAffx.67.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000041745
NCBI entrez gene - 100859339     See in Manteia.
RefSeq - XM_003642919
swissprot - R4GI22
Ensembl - ENSGALG00000027630
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 npr2ENSDARG00000104393Danio rerio
 NPR2ENSG00000159899Homo sapiens
 Npr2ENSMUSG00000028469Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000003786954
GUCY2F* / P51841* / P52785* / Q02846* / Q5SDA5* / GUCY2D* / Gucy2e* / Guanylyl cyclase GC-E * / Retinal guanylyl cyclase 2 * / guanylate cyclase 2F, retinal* / guanylate cyclase 2D, retinal*ENSGALG0000000080832
GUCY2C / guanylate cyclase 2C / P25092* / Q3UWA6* / Heat-stable enterotoxin receptor *ENSGALG0000001183829
ENSGALG0000001575327
ENSGALG0000004301415
Gucy1b2*ENSGALG0000000507615
GUCY1A2 / guanylate cyclase 1 soluble subunit alpha 2 / P33402*ENSGALG0000001717314
GUCY1B1 / guanylate cyclase 1 soluble subunit beta 1 / O54865* / Q02153* / guanylate cyclase 1, soluble, beta 1*ENSGALG0000000936114
GUCY1A1 / guanylate cyclase 1 soluble subunit alpha 1 / Q02108* / Q9ERL9* / guanylate cyclase 1, soluble, alpha 1*ENSGALG0000003594613


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001054  Adenylyl cyclase class-3/4/guanylyl cyclase
 IPR001170  Adenylyl cyclase class-4/guanylyl cyclase
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001828  Receptor, ligand binding region
 IPR011009  Protein kinase-like domain superfamily
 IPR018297  Adenylyl cyclase class-4/guanylyl cyclase, conserved site
 IPR028082  Periplasmic binding protein-like I
 IPR029787  Nucleotide cyclase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006182 cGMP biosynthetic process IBA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007168 receptor guanylyl cyclase signaling pathway IEA
 biological_processGO:0009190 cyclic nucleotide biosynthetic process IEA
 biological_processGO:0022414 reproductive process IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0051447 negative regulation of meiotic cell cycle IEA
 biological_processGO:0060348 bone development IEA
 biological_processGO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus IEA
 biological_processGO:1900194 negative regulation of oocyte maturation IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0008074 guanylate cyclase complex, soluble IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004383 guanylate cyclase activity IBA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016849 phosphorus-oxygen lyase activity IEA
 molecular_functionGO:0016941 natriuretic peptide receptor activity IEA
 molecular_functionGO:0017046 peptide hormone binding IEA
 molecular_functionGO:0042562 hormone binding IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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