ENSGALG00000012115


Gallus gallus

Features
Gene ID: ENSGALG00000012115
  
Biological name :WT1
  
Synonyms : Wilms tumor protein / WT1
  
Possible biological names infered from orthology : P19544 / Wilms tumor 1 / Wilms tumor 1 homolog
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 5439369
Gene end: 5522369
  
Corresponding Affymetrix probe sets: Gga.4294.1.S1_at (Chicken Array)   Gga.5712.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000019761
Ensembl peptide - ENSGALP00000056301
Ensembl peptide - ENSGALP00000051223
NCBI entrez gene - 101747322     See in Manteia.
RefSeq - NM_205216
RefSeq - XM_015286134
RefSeq Peptide - NP_990547
swissprot - A0A1D5PTQ2
swissprot - A0A1D5PEL8
swissprot - F1NF76
Ensembl - ENSGALG00000012115
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wt1aENSDARG00000031420Danio rerio
 wt1bENSDARG00000007990Danio rerio
 WT1ENSG00000184937Homo sapiens
 Wt1ENSMUSG00000016458Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EGR2 / early growth response 2 / P08152* / P11161* / E3 SUMO-protein ligase EGR2 *ENSGALG0000004097126
EGR1 / early growth response protein 1 / P08046* / P18146* / early growth response 1*ENSGALG0000000766925
EGR4 / early growth response 4 / Q05215* / Q9WUF2* / Early growth response protein 4 *ENSGALG0000001608621


Protein motifs (from Interpro)
Interpro ID Name
 IPR000976  Wilm"s tumour protein, N-terminal
 IPR013087  Zinc finger C2H2-type
 IPR017987  Wilm"s tumour protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISS
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis ISS
 biological_processGO:0001822 kidney development ISS
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007507 heart development ISS
 biological_processGO:0007530 sex determination ISS
 biological_processGO:0008285 negative regulation of cell proliferation ISS
 biological_processGO:0008584 male gonad development ISS
 biological_processGO:0017148 negative regulation of translation ISS
 biological_processGO:0030308 negative regulation of cell growth ISS
 biological_processGO:0030325 adrenal gland development ISS
 biological_processGO:0032835 glomerulus development ISS
 biological_processGO:0032836 glomerular basement membrane development ISS
 biological_processGO:0043065 positive regulation of apoptotic process ISS
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 biological_processGO:0061032 visceral serous pericardium development ISS
 biological_processGO:0071320 cellular response to cAMP ISS
 biological_processGO:0071371 cellular response to gonadotropin stimulus ISS
 biological_processGO:0072112 glomerular visceral epithelial cell differentiation IBA
 biological_processGO:0072207 metanephric epithelium development ISS
 biological_processGO:0072284 metanephric S-shaped body morphogenesis ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005654 nucleoplasm ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0016607 nuclear speck ISS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0008270 zinc ion binding ISS
 molecular_functionGO:0010385 double-stranded methylated DNA binding ISS
 molecular_functionGO:0043565 sequence-specific DNA binding ISS
 molecular_functionGO:0044212 transcription regulatory region DNA binding ISS
 molecular_functionGO:0044729 hemi-methylated DNA-binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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