ENSGALG00000012275


Gallus gallus

Features
Gene ID: ENSGALG00000012275
  
Biological name :EPM2A
  
Synonyms : EPM2A / EPM2A, laforin glucan phosphatase
  
Possible biological names infered from orthology : Laforin / O95278 / Q9WUA5
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 46623966
Gene end: 46663960
  
Corresponding Affymetrix probe sets: GgaAffx.11991.1.S1_at (Chicken Array)   GgaAffx.7776.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000031170
NCBI entrez gene - 421611     See in Manteia.
RefSeq - NM_001031069
RefSeq Peptide - NP_001026240
swissprot - Q5ZL46
Ensembl - ENSGALG00000012275
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 epm2aENSDARG00000059044Danio rerio
 EPM2AENSG00000112425Homo sapiens
 Epm2aENSMUSG00000055493Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR002044  Carbohydrate binding module family 20
 IPR013783  Immunoglobulin-like fold
 IPR013784  Carbohydrate-binding-like fold
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR020422  Dual specificity protein phosphatase domain
 IPR024950  Dual specificity phosphatase
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005977 glycogen metabolic process IEA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0016239 positive regulation of macroautophagy IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0046838 phosphorylated carbohydrate dephosphorylation IEA
 biological_processGO:0046959 habituation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005844 polysome IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0019203 carbohydrate phosphatase activity IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:2001069 glycogen binding IEA
 molecular_functionGO:2001070 starch binding IEA


Pathways (from Reactome)
Pathway description
Glycogen synthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000013265 GYS2 / glycogen synthase 2 / P54840* / Q8VCB3* / Glycogen [starch] synthase, liver *  / reaction
 ENSGALG00000012275 EPM2A / EPM2A, laforin glucan phosphatase / O95278* / Q9WUA5* / Laforin *  / complex






 

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