ENSGALG00000012448


Gallus gallus

Features
Gene ID: ENSGALG00000012448
  
Biological name :ORC4
  
Synonyms : ORC4 / origin recognition complex subunit 4
  
Possible biological names infered from orthology : Mus musculus origin recognition complex, subunit 4 (Orc4), transcript variant 4, mRNA. / O43929 / O88708
  
Species: Gallus gallus
  
Chr. number: 7
Strand: -1
Band:
Gene start: 34746169
Gene end: 34759741
  
Corresponding Affymetrix probe sets: Gga.7431.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000020323
Ensembl peptide - ENSGALP00000064547
Ensembl peptide - ENSGALP00000062375
Ensembl peptide - ENSGALP00000062144
Ensembl peptide - ENSGALP00000058844
Ensembl peptide - ENSGALP00000057681
Ensembl peptide - ENSGALP00000056290
NCBI entrez gene - 424307     See in Manteia.
RefSeq - XM_015289886
RefSeq - XM_422152
swissprot - A0A1L1RU83
swissprot - A0A1L1RTJ5
swissprot - E1C8I5
swissprot - A0A1D5PXI6
swissprot - A0A1D5PTP1
swissprot - A0A1L1RJC4
swissprot - A0A1L1S090
Ensembl - ENSGALG00000012448
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 orc4ENSDARG00000101161Danio rerio
 ORC4ENSG00000115947Homo sapiens
 Orc4ENSMUSG00000026761Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR016527  Origin recognition complex subunit 4
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR032705  Origin recognition complex subunit 4, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006270 DNA replication initiation IEA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IEA
 cellular_componentGO:0000808 origin recognition complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005664 nuclear origin of replication recognition complex IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003688 DNA replication origin binding IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
Assembly of the ORC complex at the origin of replication
CDC6 association with the ORC:origin complex
CDT1 association with the CDC6:ORC:origin complex
Assembly of the pre-replicative complex
Orc1 removal from chromatin
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr