ENSGALG00000012483


Gallus gallus

Features
Gene ID: ENSGALG00000012483
  
Biological name :TMPRSS6
  
Synonyms : TMPRSS6 / transmembrane serine protease 6
  
Possible biological names infered from orthology : Mus musculus transmembrane serine protease 6 (Tmprss6), transcript variant 2, mRNA. / Q8IU80 / Q9DBI0
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 51508827
Gene end: 51526284
  
Corresponding Affymetrix probe sets: GgaAffx.7919.1.S1_at (Chicken Array)   GgaAffx.7919.2.S1_at (Chicken Array)   GgaAffx.7919.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000020367
NCBI entrez gene - 418046     See in Manteia.
RefSeq - XM_004937765
RefSeq - XM_004937766
RefSeq - XM_004937767
swissprot - F1NDU7
Ensembl - ENSGALG00000012483
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q8IU80ENSG00000187045Homo sapiens
 Q9DBI0ENSMUSG00000016942Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ST14 / suppression of tumorigenicity 14 / P56677* / Q9Y5Y6* / suppression of tumorigenicity 14 (colon carcinoma)*ENSGALG0000000133130
TMPRSS7 / transmembrane serine protease 7 / Q7RTY8* / Q8BIK6* / Transmembrane protease serine 7 *ENSGALG0000001538928
ENSGALG0000001922122
CORIN / corin, serine peptidase / Q9Y5Q5* / Q9Z319* / Atrial natriuretic peptide-converting enzyme Atrial natriuretic peptide-converting enzyme, N-terminal propeptide Atrial natriuretic pep...ENSGALG0000001414422
TMPRSS15 / transmembrane serine protease 15 / P97435* / P98073* / transmembrane protease, serine 15*ENSGALG0000001573019
TMPRSS9 / transmembrane serine protease 9 / Q7Z410* / transmembrane protease, serine 9*ENSGALG0000000045819
TMPRSS3 / transmembrane serine protease 3 / P57727* / Q8K1T0* / transmembrane protease, serine 3*ENSGALG0000001616917
F11* / KLKB1* / Q91Y47* / P03951* / P03952* / P26262* / kallikrein B1* / coagulation factor XI* / Plasma kallikrein Plasma kallikrein heavy chain Plasma kallikrein light chain* / Coagulatio...ENSGALG0000001357117
TMPRSS13 / transmembrane serine protease 13 / Q9BYE2*ENSGALG0000002127317
TMPRSS2 / transmembrane serine protease 2 / O15393* / Q9JIQ8* / Transmembrane protease serine 2 Transmembrane protease serine 2 non-catalytic chain Transmembrane protease serine 2 catalytic chain*ENSGALG0000001614416
TMPRSS4 / transmembrane serine protease 4 / Q8VCA5* / Q9NRS4* / Transmembrane protease serine 4 *ENSGALG0000000740614


Protein motifs (from Interpro)
Interpro ID Name
 IPR000082  SEA domain
 IPR000859  CUB domain
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR002172  Low-density lipoprotein (LDL) receptor class A repeat
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR023415  Low-density lipoprotein (LDL) receptor class A, conserved site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006879 cellular iron ion homeostasis IEA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IEA
 biological_processGO:0033619 membrane protein proteolysis IEA
 biological_processGO:0042730 fibrinolysis IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0055072 iron ion homeostasis IEA
 biological_processGO:0097264 self proteolysis IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Degradation of the extracellular matrix


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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