ENSGALG00000012606


Gallus gallus

Features
Gene ID: ENSGALG00000012606
  
Biological name :ISCA1
  
Synonyms : Iron-sulfur cluster assembly 1 homolog, mitochondrial / ISCA1 / Q5ZJ74
  
Possible biological names infered from orthology : AK157302 / cDNA sequence AK157302 / iron-sulfur cluster assembly 1 / Q9BUE6 / Q9D924
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 40820633
Gene end: 40827561
  
Corresponding Affymetrix probe sets: Gga.17293.1.S1_s_at (Chicken Array)   Gga.8072.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000060186
Ensembl peptide - ENSGALP00000020553
NCBI entrez gene - 427463     See in Manteia.
RefSeq - NM_001271936
RefSeq Peptide - NP_001258865
swissprot - Q5ZJ74
swissprot - A0A1L1RN15
Ensembl - ENSGALG00000012606
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 isca1ENSDARG00000051956Danio rerio
 ISCA1ENSG00000135070Homo sapiens
 AK157302ENSMUSG00000078139Mus musculus
 Isca1ENSMUSG00000044792Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000361  FeS cluster biogenesis
 IPR016092  FeS cluster insertion protein
 IPR017870  FeS cluster insertion, C-terminal, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016226 iron-sulfur cluster assembly IBA
 biological_processGO:0097428 protein maturation by iron-sulfur cluster transfer IBA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix IBA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0008198 ferrous iron binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051537 2 iron, 2 sulfur cluster binding IBA


Pathways (from Reactome)
Pathway description
Mitochondrial iron-sulfur cluster biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000020417 ISCA2 / iron-sulfur cluster assembly 2 / Q86U28* / Q9DCB8* / Iron-sulfur cluster assembly 2 homolog, mitochondrial *  / complex
 ENSGALG00000011079 GLRX5 / glutaredoxin 5 / Q80Y14* / Q86SX6* / Glutaredoxin-related protein 5, mitochondrial *  / reaction






 

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contact: otassy@igbmc.fr