ENSGALG00000012992


Gallus gallus

Features
Gene ID: ENSGALG00000012992
  
Biological name :WNK1
  
Synonyms : WNK1 / WNK lysine deficient protein kinase 1
  
Possible biological names infered from orthology : P83741 / Q9H4A3
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 60503911
Gene end: 60601007
  
Corresponding Affymetrix probe sets: Gga.12178.1.S1_at (Chicken Array)   GgaAffx.24083.1.S1_s_at (Chicken Array)   GgaAffx.8231.1.S1_s_at (Chicken Array)   GgaAffx.8232.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000021178
NCBI entrez gene - 427925     See in Manteia.
RefSeq - XM_015286695
RefSeq - XM_015286704
RefSeq - XM_015286715
RefSeq - XM_015286721
RefSeq - XM_015286729
RefSeq - XM_015286737
RefSeq - XM_015286744
RefSeq - XM_015286751
RefSeq - XM_015286692
swissprot - E1BQS4
Ensembl - ENSGALG00000012992
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wnk1aENSDARG00000078992Danio rerio
 wnk1bENSDARG00000039392Danio rerio
 WNK1ENSG00000060237Homo sapiens
 Wnk1ENSMUSG00000045962Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WNK2 / WNK lysine deficient protein kinase 2 / Q9Y3S1*ENSGALG0000003885030
WNK4 / WNK lysine deficient protein kinase 4 / Q80UE6* / Q96J92*ENSGALG0000003219120
NRBP1 / nuclear receptor-binding protein / Q99J45* / Q9UHY1* / nuclear receptor binding protein 1* / Mus musculus nuclear receptor binding protein 1 (Nrbp1), transcript variant 1, mRNA.*ENSGALG000000165126
NRBP2 / nuclear receptor binding protein 2 / Q91V36* / Q9NSY0* / Mus musculus nuclear receptor binding protein 2 (Nrbp2), transcript variant 1, mRNA.*ENSGALG000000297604


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR024678  Serine/threonine-protein kinase OSR1/WNK, CCT domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003084 positive regulation of systemic arterial blood pressure IEA
 biological_processGO:0006468 protein phosphorylation IBA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0010923 negative regulation of phosphatase activity IEA
 biological_processGO:0023016 signal transduction by trans-phosphorylation IEA
 biological_processGO:0032147 activation of protein kinase activity IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0050794 regulation of cellular process IEA
 biological_processGO:0090188 negative regulation of pancreatic juice secretion IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019869 chloride channel inhibitor activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0019902 phosphatase binding IEA
 molecular_functionGO:0030295 protein kinase activator activity IEA


Pathways (from Reactome)
Pathway description
Stimuli-sensing channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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