ENSGALG00000038850


Gallus gallus

Features
Gene ID: ENSGALG00000038850
  
Biological name :WNK2
  
Synonyms : WNK2 / WNK lysine deficient protein kinase 2
  
Possible biological names infered from orthology : Q9Y3S1
  
Species: Gallus gallus
  
Chr. number: 12
Strand: -1
Band:
Gene start: 6472769
Gene end: 6578709
  
Corresponding Affymetrix probe sets: Gga.19399.1.S1_at (Chicken Array)   GgaAffx.26449.3.S1_s_at (Chicken Array)   GgaAffx.3255.1.S1_at (Chicken Array)   GgaAffx.3255.1.S1_s_at (Chicken Array)   GgaAffx.3257.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046015
Ensembl peptide - ENSGALP00000053680
Ensembl peptide - ENSGALP00000052263
Ensembl peptide - ENSGALP00000052186
Ensembl peptide - ENSGALP00000050512
Ensembl peptide - ENSGALP00000049717
Ensembl peptide - ENSGALP00000048208
NCBI entrez gene - 415984     See in Manteia.
RefSeq - XM_015293432
RefSeq - XM_015293424
RefSeq - XM_015293425
RefSeq - XM_015293426
RefSeq - XM_015293427
RefSeq - XM_015293428
RefSeq - XM_015293429
RefSeq - XM_015293431
RefSeq - XM_015293416
RefSeq - XM_015293417
RefSeq - XM_015293420
RefSeq - XM_015293421
RefSeq - XM_015293422
RefSeq - XM_015293423
swissprot - A0A1D5PHI4
swissprot - A0A1D5PHA9
swissprot - A0A1D5PCM3
swissprot - A0A1D5PAF4
swissprot - A0A1D5P684
swissprot - A0A1D5P041
swissprot - A0A1D5PLG4
Ensembl - ENSGALG00000038850
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wnk2ENSDARG00000104989Danio rerio
 WNK2ENSG00000165238Homo sapiens
 Wnk2ENSMUSG00000037989Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WNK1 / WNK lysine deficient protein kinase 1 / P83741* / Q9H4A3*ENSGALG0000001299232
WNK4 / WNK lysine deficient protein kinase 4 / Q80UE6* / Q96J92*ENSGALG0000003219120
NRBP1 / nuclear receptor-binding protein / Q99J45* / Q9UHY1* / nuclear receptor binding protein 1* / Mus musculus nuclear receptor binding protein 1 (Nrbp1), transcript variant 1, mRNA.*ENSGALG000000165126
NRBP2 / nuclear receptor binding protein 2 / Q91V36* / Q9NSY0* / Mus musculus nuclear receptor binding protein 2 (Nrbp2), transcript variant 1, mRNA.*ENSGALG000000297604


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR024678  Serine/threonine-protein kinase OSR1/WNK, CCT domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 biological_processGO:2000651 positive regulation of sodium ion transmembrane transporter activity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Stimuli-sensing channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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