ENSMUSG00000037989


Mus musculus

Features
Gene ID: ENSMUSG00000037989
  
Biological name :Wnk2
  
Synonyms : Wnk2 / WNK lysine deficient protein kinase 2
  
Possible biological names infered from orthology : Q9Y3S1
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: A5
Gene start: 49036303
Gene end: 49148014
  
Corresponding Affymetrix probe sets: 10409118 (MoGene1.0st)   1443423_at (Mouse Genome 430 2.0 Array)   1453355_at (Mouse Genome 430 2.0 Array)   1455424_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000105723
Ensembl peptide - ENSMUSP00000089212
Ensembl peptide - ENSMUSP00000105724
Ensembl peptide - ENSMUSP00000125539
Ensembl peptide - ENSMUSP00000125522
Ensembl peptide - ENSMUSP00000125448
Ensembl peptide - ENSMUSP00000124614
Ensembl peptide - ENSMUSP00000124598
Ensembl peptide - ENSMUSP00000123915
Ensembl peptide - ENSMUSP00000047231
Ensembl peptide - ENSMUSP00000049327
NCBI entrez gene - 75607     See in Manteia.
MGI - MGI:1922857
RefSeq - XM_017315627
RefSeq - XM_011244416
RefSeq - XM_011244417
RefSeq - XM_011244418
RefSeq - XM_011244419
RefSeq - XM_011244420
RefSeq - XM_011244421
RefSeq - XM_011244422
RefSeq - XM_011244423
RefSeq - XM_011244424
RefSeq - XM_011244425
RefSeq - XM_011244426
RefSeq - XM_011244427
RefSeq - XM_017315626
RefSeq - NM_001290311
RefSeq - NM_001290313
RefSeq - NM_029361
RefSeq - XM_006516974
RefSeq - XM_006516977
RefSeq - XM_006516979
RefSeq - XM_011244415
RefSeq Peptide - NP_083637
RefSeq Peptide - NP_001277242
RefSeq Peptide - NP_001277240
swissprot - E9QJQ9
swissprot - E9Q6Q2
swissprot - E0CZE3
swissprot - E9QMI9
swissprot - F7BQG5
swissprot - E0CYT1
swissprot - A0A0R4J1Z1
swissprot - F6SRP4
swissprot - E9QMI8
swissprot - E9QM73
Ensembl - ENSMUSG00000037989
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wnk2ENSDARG00000104989Danio rerio
 WNK2ENSGALG00000038850Gallus gallus
 WNK2ENSG00000165238Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Wnk1 / P83741 / WNK lysine deficient protein kinase 1 / Q9H4A3*ENSMUSG0000004596232
Wnk3 / Q80XP9 / WNK lysine deficient protein kinase 3 / Q9BYP7*ENSMUSG0000004124529
Wnk4 / Q80UE6 / WNK lysine deficient protein kinase 4 / Q96J92*ENSMUSG0000003511222
Nrbp1 / Q99J45 / Mus musculus nuclear receptor binding protein 1 (Nrbp1), transcript variant 1, mRNA. / Q9UHY1* / nuclear receptor binding protein 1*ENSMUSG000000291487
Nrbp2 / Q91V36 / Mus musculus nuclear receptor binding protein 2 (Nrbp2), transcript variant 1, mRNA. / Q9NSY0* / nuclear receptor binding protein 2*ENSMUSG000000755903


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR024678  Serine/threonine-protein kinase OSR1/WNK, CCT domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 biological_processGO:2000651 positive regulation of sodium ion transmembrane transporter activity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Stimuli-sensing channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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