ENSGALG00000013605


Gallus gallus

Features
Gene ID: ENSGALG00000013605
  
Biological name :CARMIL1
  
Synonyms : CARMIL1 / F-actin-uncapping protein LRRC16A
  
Possible biological names infered from orthology : capping protein regulator and myosin 1 linker 1 / Q5VZK9 / Q6EDY6
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 90220685
Gene end: 90394975
  
Corresponding Affymetrix probe sets: Gga.13242.1.S1_s_at (Chicken Array)   Gga.13727.1.S1_at (Chicken Array)   Gga.19512.1.S1_at (Chicken Array)   Gga.7907.1.S1_at (Chicken Array)   GgaAffx.24232.1.S1_at (Chicken Array)   GgaAffx.24232.2.S1_s_at (Chicken Array)   GgaAffx.24232.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000022096
Ensembl peptide - ENSGALP00000056293
Ensembl peptide - ENSGALP00000056037
Ensembl peptide - ENSGALP00000047393
Ensembl peptide - ENSGALP00000044835
Ensembl peptide - ENSGALP00000044034
NCBI entrez gene - 421002     See in Manteia.
RefSeq - NM_001159370
RefSeq Peptide - NP_001152842
swissprot - A0A1D5P3Y7
swissprot - A0A1D5NWU2
swissprot - A0A1D5PTP4
swissprot - F1NWT4
swissprot - A0A1D5NUL6
swissprot - A0A1D5PSZ7
Ensembl - ENSGALG00000013605
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 carmil1ENSDARG00000103887Danio rerio
 Q5VZK9ENSG00000079691Homo sapiens
 Q6EDY6ENSMUSG00000021338Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CARMIL2 / capping protein regulator and myosin 1 linker 2 / Q3V3V9* / Q6F5E8* / Mus musculus capping protein regulator and myosin 1 linker 2 (Carmil2), mRNA.*ENSGALG0000002144234


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR029764  Leucine-rich repeat-containing protein 16A
 IPR031943  CARMIL, C-terminal domain
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0030032 lamellipodium assembly IEA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0030838 positive regulation of actin filament polymerization IEA
 biological_processGO:0031529 ruffle organization IEA
 biological_processGO:0044351 macropinocytosis IEA
 biological_processGO:0046415 urate metabolic process IEA
 biological_processGO:0051496 positive regulation of stress fiber assembly IEA
 biological_processGO:0051638 barbed-end actin filament uncapping IEA
 biological_processGO:0051639 actin filament network formation IEA
 biological_processGO:1900026 positive regulation of substrate adhesion-dependent cell spreading IEA
 biological_processGO:1902745 positive regulation of lamellipodium organization IEA
 biological_processGO:2000813 negative regulation of barbed-end actin filament capping IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0031252 cell leading edge IEA
 cellular_componentGO:0031941 filamentous actin IEA
 cellular_componentGO:0044354 macropinosome IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA


Pathways (from Reactome)
Pathway description
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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