ENSGALG00000014858


Gallus gallus

Features
Gene ID: ENSGALG00000014858
  
Biological name :ADCYAP1
  
Synonyms : ADCYAP1 / adenylate cyclase activating polypeptide 1
  
Possible biological names infered from orthology : O70176 / P18509
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 102121710
Gene end: 102124573
  
Corresponding Affymetrix probe sets: Gga.11409.1.S1_at (Chicken Array)   Gga.616.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000023931
Ensembl peptide - ENSGALP00000062803
Ensembl peptide - ENSGALP00000062517
Ensembl peptide - ENSGALP00000046043
NCBI entrez gene - 408251     See in Manteia.
RefSeq - NM_001001291
RefSeq Peptide - NP_001001291
swissprot - A0A1L1RVE9
swissprot - A0A1L1RUL5
swissprot - A0A1D5P069
swissprot - Q58FG9
Ensembl - ENSGALG00000014858
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adcyap1aENSDARG00000004015Danio rerio
 adcyap1bENSDARG00000027740Danio rerio
 P18509ENSG00000141433Homo sapiens
 O70176ENSMUSG00000024256Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
VIP / P48143 / VIP peptides Intestinal peptide PHI-27-like Vasoactive intestinal peptide / P01282* / vasoactive intestinal peptide* / vasoactive intestinal polypeptide*ENSGALG0000001360434


Protein motifs (from Interpro)
Interpro ID Name
 IPR000532  Glucagon/GIP/secretin/VIP


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0008277 regulation of G-protein coupled receptor protein signaling pathway IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0019933 cAMP-mediated signaling IEA
 biological_processGO:0030073 insulin secretion IEA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0032880 regulation of protein localization IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0045786 negative regulation of cell cycle IEA
 biological_processGO:0045860 positive regulation of protein kinase activity IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0043005 neuron projection IDA
 cellular_componentGO:0043204 perikaryon IDA
 cellular_componentGO:0044297 cell body IDA
 cellular_componentGO:0070852 cell body fiber IDA
 molecular_functionGO:0005057 obsolete signal transducer activity, downstream of receptor IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0005184 neuropeptide hormone activity IEA
 molecular_functionGO:0016521 pituitary adenylate cyclase activating polypeptide activity IEA
 molecular_functionGO:0051428 peptide hormone receptor binding IEA


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events
Glucagon-type ligand receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000005223 ADCYAP1R1 / ADCYAP receptor type I / P41586* / P70205* / adenylate cyclase activating polypeptide 1 receptor 1*  / complex / reaction






 

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contact: otassy@igbmc.fr