ENSGALG00000014862


Gallus gallus

Features
Gene ID: ENSGALG00000014862
  
Biological name :HMGCS1
  
Synonyms : HMGCS1 / hydroxymethylglutaryl-CoA synthase, cytoplasmic
  
Possible biological names infered from orthology : 3-hydroxy-3-methylglutaryl-CoA synthase 1 / Q01581 / Q8JZK9
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 13655405
Gene end: 13665325
  
Corresponding Affymetrix probe sets: Gga.15337.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000023936
Ensembl peptide - ENSGALP00000064148
NCBI entrez gene - 396379     See in Manteia.
RefSeq - XM_015277256
RefSeq - NM_205411
RefSeq - XM_015277254
RefSeq - XM_015277255
RefSeq - XM_015277252
RefSeq - XM_015277253
RefSeq Peptide - NP_990742
swissprot - F1N9T0
Ensembl - ENSGALG00000014862
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hmgcs1ENSDARG00000103025Danio rerio
 HMGCS1ENSG00000112972Homo sapiens
 Hmgcs1ENSMUSG00000093930Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HMGCS2 / 3-hydroxy-3-methylglutaryl-CoA synthase 2 / P54868* / P54869* / Hydroxymethylglutaryl-CoA synthase, mitochondrial *ENSGALG0000000296065


Protein motifs (from Interpro)
Interpro ID Name
 IPR000590  Hydroxymethylglutaryl-coenzyme A synthase, active site
 IPR010122  Hydroxymethylglutaryl-CoA synthase, eukaryotic
 IPR013528  Hydroxymethylglutaryl-coenzyme A synthase, N-terminal
 IPR013746  Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain
 IPR016039  Thiolase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006694 steroid biosynthetic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0008202 steroid metabolic process IEA
 biological_processGO:0008299 isoprenoid biosynthetic process IEA
 biological_processGO:0016126 sterol biosynthetic process IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004421 hydroxymethylglutaryl-CoA synthase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Cholesterol biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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