ENSGALG00000015664


Gallus gallus

Features
Gene ID: ENSGALG00000015664
  
Biological name :ADD1
  
Synonyms : ADD1 / adducin 1
  
Possible biological names infered from orthology : Mus musculus adducin 1 (alpha) (Add1), transcript variant 5, mRNA. / P35611 / Q9QYC0
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 82871401
Gene end: 82928604
  
Corresponding Affymetrix probe sets: Gga.1238.1.S1_at (Chicken Array)   GgaAffx.9982.1.S1_at (Chicken Array)   GgaAffx.9982.4.S1_at (Chicken Array)   GgaAffx.9982.4.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000063337
Ensembl peptide - ENSGALP00000025213
NCBI entrez gene - 422882     See in Manteia.
RefSeq - XM_015285778
RefSeq - XM_015285775
RefSeq - XM_015285776
RefSeq - XM_015285777
RefSeq - NM_001079730
RefSeq - XM_015285766
RefSeq - XM_015285767
RefSeq - XM_015285768
RefSeq - XM_015285769
RefSeq - XM_015285771
RefSeq - XM_015285772
RefSeq - XM_015285773
RefSeq - XM_015285774
RefSeq Peptide - NP_001073198
swissprot - F1ND55
swissprot - A0A1L1RWX3
Ensembl - ENSGALG00000015664
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 add1ENSDARG00000103962Danio rerio
 ADD1ENSG00000087274Homo sapiens
 Add1ENSMUSG00000029106Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADD3 / gamma-adducin / Q9QYB5* / Q9UEY8* / adducin 3*ENSGALG0000000854251
ADD2 / adducin 2 / P35612* / Q9QYB8* / Beta-adducin *ENSGALG0000002694844


Protein motifs (from Interpro)
Interpro ID Name
 IPR001303  Class II aldolase/adducin N-terminal
 IPR027766  Alpha-adducin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000902 cell morphogenesis IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006884 cell volume homeostasis IEA
 biological_processGO:0020027 hemoglobin metabolic process IEA
 biological_processGO:0030218 erythrocyte differentiation IEA
 biological_processGO:0032092 positive regulation of protein binding IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0048873 homeostasis of number of cells within a tissue IEA
 biological_processGO:0051016 barbed-end actin filament capping IEA
 biological_processGO:0051017 actin filament bundle assembly IEA
 biological_processGO:0071277 cellular response to calcium ion IEA
 biological_processGO:1903142 positive regulation of establishment of endothelial barrier IEA
 biological_processGO:1903393 positive regulation of adherens junction organization IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005913 cell-cell adherens junction IEA
 cellular_componentGO:0008290 F-actin capping protein complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016604 nuclear body IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0030507 spectrin binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
Caspase-mediated cleavage of cytoskeletal proteins
Miscellaneous transport and binding events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008542 ADD3 / gamma-adducin / Q9QYB5* / Q9UEY8* / adducin 3*  / complex
 ENSGALG00000010638 CASP3 / caspase 3 / P42574* / P70677* / Caspase-3 Caspase-3 subunit p17 Caspase-3 subunit p12*  / reaction






 

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