ENSGALG00000016438


Gallus gallus

Features
Gene ID: ENSGALG00000016438
  
Biological name :MELK
  
Synonyms : maternal embryonic leucine zipper kinase / MELK
  
Possible biological names infered from orthology : Q14680 / Q61846
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 81980862
Gene end: 82003287
  
Corresponding Affymetrix probe sets: GgaAffx.10518.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000026466
Ensembl peptide - ENSGALP00000062582
Ensembl peptide - ENSGALP00000048443
Ensembl peptide - ENSGALP00000048083
NCBI entrez gene - 428391     See in Manteia.
RefSeq - NM_001031509
RefSeq - XM_015280794
RefSeq Peptide - NP_001026680
swissprot - A0A1L1RUT3
swissprot - F1NKU2
swissprot - A0A1D5P6W2
swissprot - A0A1D5P5W0
Ensembl - ENSGALG00000016438
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 melkENSDARG00000030759Danio rerio
 MELKENSG00000165304Homo sapiens
 MelkENSMUSG00000035683Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HUNK / hormonally up-regulated Neu-associated kinase / O88866* / P57058* / Hormonally up-regulated neu tumor-associated kinase *ENSGALG0000001587920
ENSGALG0000002856617


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001772  Kinase associated domain 1 (KA1)
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR028375  KA1 domain/Ssp2, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0061351 neural precursor cell proliferation IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005938 cell cortex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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