ENSGALG00000016491


Gallus gallus

Features
Gene ID: ENSGALG00000016491
  
Biological name :APOB
  
Synonyms : APOB / apolipoprotein B precursor
  
Possible biological names infered from orthology : apolipoprotein B / Apolipoprotein B-100 Apolipoprotein B-48 / E9Q414 / P04114
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 102659050
Gene end: 102693303
  
Corresponding Affymetrix probe sets: Gga.11817.1.S1_s_at (Chicken Array)   Gga.20079.1.S1_s_at (Chicken Array)   Gga.4112.1.S1_at (Chicken Array)   Gga.6583.1.S1_at (Chicken Array)   GgaAffx.24973.1.S1_at (Chicken Array)   GgaAffx.24974.1.S1_at (Chicken Array)   GgaAffx.24976.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000026550
NCBI entrez gene - 396535     See in Manteia.
RefSeq - NM_001044633
RefSeq Peptide - NP_001038098
swissprot - F1NV02
Ensembl - ENSGALG00000016491
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 apobaENSDARG00000042780Danio rerio
 apobb.1ENSDARG00000022767Danio rerio
 apobb.2ENSDARG00000075016Danio rerio
 APOBENSG00000084674Homo sapiens
 ApobENSMUSG00000020609Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001747  Lipid transport protein, N-terminal
 IPR009454  Lipid transport, open beta-sheet
 IPR011030  Lipovitellin-phosvitin complex, superhelical domain
 IPR015255  Vitellinogen, open beta-sheet
 IPR015816  Vitellinogen, beta-sheet N-terminal
 IPR015817  Vitellinogen, open beta-sheet, subdomain 1
 IPR015819  Lipid transport protein, beta-sheet shell
 IPR022176  Apolipoprotein B100 C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006642 triglyceride mobilization IEA
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0008203 cholesterol metabolic process IEA
 biological_processGO:0009566 fertilization IEA
 biological_processGO:0009615 response to virus IEA
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010744 positive regulation of macrophage derived foam cell differentiation IEA
 biological_processGO:0010884 positive regulation of lipid storage IEA
 biological_processGO:0010886 positive regulation of cholesterol storage IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0019433 triglyceride catabolic process IEA
 biological_processGO:0030301 cholesterol transport IEA
 biological_processGO:0030317 flagellated sperm motility IEA
 biological_processGO:0033344 cholesterol efflux IEA
 biological_processGO:0034374 low-density lipoprotein particle remodeling IEA
 biological_processGO:0034383 low-density lipoprotein particle clearance IEA
 biological_processGO:0042157 lipoprotein metabolic process IEA
 biological_processGO:0042158 lipoprotein biosynthetic process IEA
 biological_processGO:0042159 lipoprotein catabolic process IEA
 biological_processGO:0042632 cholesterol homeostasis IEA
 biological_processGO:0042953 lipoprotein transport IEA
 biological_processGO:0045540 regulation of cholesterol biosynthetic process IEA
 biological_processGO:0048844 artery morphogenesis IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0034359 mature chylomicron IEA
 cellular_componentGO:0034361 very-low-density lipoprotein particle IEA
 cellular_componentGO:0034362 low-density lipoprotein particle IEA
 cellular_componentGO:0034363 intermediate-density lipoprotein particle IEA
 cellular_componentGO:0042627 chylomicron IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0070971 endoplasmic reticulum exit site IEA
 molecular_functionGO:0005319 lipid transporter activity IEA
 molecular_functionGO:0005543 phospholipid binding IEA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0017127 cholesterol transporter activity IEA
 molecular_functionGO:0035473 lipase binding IEA
 molecular_functionGO:0050750 low-density lipoprotein particle receptor binding IEA


Pathways (from Reactome)
Pathway description
Scavenging by Class B Receptors
Scavenging by Class A Receptors
Scavenging by Class H Receptors
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Platelet sensitization by LDL
Regulation of TLR by endogenous ligand
VLDL assembly
Post-translational protein phosphorylation
Chylomicron assembly
LDL clearance
LDL remodeling
Retinoid metabolism and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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