ENSGALG00000016781


Gallus gallus

Features
Gene ID: ENSGALG00000016781
  
Biological name :MAP4K4
  
Synonyms : MAP4K4 / mitogen-activated protein kinase kinase kinase kinase 4
  
Possible biological names infered from orthology : O95819
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 133742880
Gene end: 133800008
  
Corresponding Affymetrix probe sets: Gga.4757.1.S1_at (Chicken Array)   GgaAffx.25074.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000008090
Ensembl peptide - ENSGALP00000054441
Ensembl peptide - ENSGALP00000048858
Ensembl peptide - ENSGALP00000046317
Ensembl peptide - ENSGALP00000045696
Ensembl peptide - ENSGALP00000044412
NCBI entrez gene - 418714     See in Manteia.
RefSeq - XM_015277809
RefSeq - XM_015277802
RefSeq - XM_015277803
RefSeq - XM_015277805
RefSeq - XM_015277806
RefSeq - XM_015277807
RefSeq - XM_015277808
RefSeq - XM_015277799
RefSeq - XM_015277800
RefSeq - XM_015277801
swissprot - A0A1D5PNJ9
swissprot - A0A1D5P813
swissprot - A0A1D5P0Y7
swissprot - A0A1D5NZ81
swissprot - A0A1D5NVN6
swissprot - E1BRQ3
Ensembl - ENSGALG00000016781
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 map4k4ENSDARG00000098670Danio rerio
 MAP4K4ENSG00000071054Homo sapiens
 Map4k4ENSMUSG00000026074Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TNIK / TRAF2 and NCK interacting kinase / P83510* / Q9UKE5*ENSGALG0000000929868
NRK / nik-related protein kinase / Q7Z2Y5* / Q9R0G8* / Nik related kinase*ENSGALG0000000897054
MAP4K3 / mitogen-activated protein kinase kinase kinase kinase 3 / Q8IVH8* / Q99JP0*ENSGALG0000003972020
MAP4K5 / mitogen-activated protein kinase kinase kinase kinase 5 / Q8BPM2*ENSGALG0000001232117
SLK / STE20 like kinase / O54988* / Q9H2G2* / STE20-like serine/threonine-protein kinase *ENSGALG0000000831816
STK10 / F1NBT0 / Serine/threonine-protein kinase 10 / O94804* / O55098* / serine/threonine kinase 10*ENSGALG0000000281615


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001180  Citron homology (CNH) domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0000185 activation of MAPKKK activity IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0046328 regulation of JNK cascade IEA
 biological_processGO:0048812 neuron projection morphogenesis IBA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004111 creatine kinase activity IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008349 MAP kinase kinase kinase kinase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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