ENSGALG00000009298


Gallus gallus

Features
Gene ID: ENSGALG00000009298
  
Biological name :TNIK
  
Synonyms : TNIK / TRAF2 and NCK interacting kinase
  
Possible biological names infered from orthology : P83510 / Q9UKE5
  
Species: Gallus gallus
  
Chr. number: 9
Strand: 1
Band:
Gene start: 19651404
Gene end: 19784548
  
Corresponding Affymetrix probe sets: GgaAffx.22872.1.S1_s_at (Chicken Array)   GgaAffx.22872.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000015110
Ensembl peptide - ENSGALP00000054149
Ensembl peptide - ENSGALP00000051344
Ensembl peptide - ENSGALP00000044429
NCBI entrez gene - 424987     See in Manteia.
RefSeq - XM_015291719
RefSeq - XM_015291715
RefSeq - XM_015291716
RefSeq - XM_015291717
RefSeq - XM_015291718
swissprot - A0A1D5PEY2
swissprot - A0A1D5NVQ3
swissprot - F1P3F8
swissprot - A0A1D5PMR2
Ensembl - ENSGALG00000009298
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tnikaENSDARG00000056218Danio rerio
 tnikbENSDARG00000009031Danio rerio
 TNIKENSG00000154310Homo sapiens
 TnikENSMUSG00000027692Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAP4K4 / mitogen-activated protein kinase kinase kinase kinase 4 / O95819*ENSGALG0000001678163
NRK / nik-related protein kinase / Q7Z2Y5* / Q9R0G8* / Nik related kinase*ENSGALG0000000897051
MAP4K3 / mitogen-activated protein kinase kinase kinase kinase 3 / Q8IVH8* / Q99JP0*ENSGALG0000003972020
MAP4K5 / mitogen-activated protein kinase kinase kinase kinase 5 / Q8BPM2*ENSGALG0000001232117
SLK / STE20 like kinase / O54988* / Q9H2G2* / STE20-like serine/threonine-protein kinase *ENSGALG0000000831816
STK10 / F1NBT0 / Serine/threonine-protein kinase 10 / O94804* / O55098* / serine/threonine kinase 10*ENSGALG0000000281616


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001180  Citron homology (CNH) domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000185 activation of MAPKKK activity IEA
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0007256 activation of JNKK activity IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0030033 microvillus assembly IEA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0031532 actin cytoskeleton reorganization IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0048812 neuron projection morphogenesis IBA
 biological_processGO:0048814 regulation of dendrite morphogenesis IEA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008349 MAP kinase kinase kinase kinase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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