ENSDARG00000009031


Danio rerio

Features
Gene ID: ENSDARG00000009031
  
Biological name :tnikb
  
Synonyms : tnikb / TRAF2 and NCK interacting kinase b
  
Possible biological names infered from orthology : P83510 / Q9UKE5 / TNIK / TRAF2 and NCK interacting kinase
  
Species: Danio rerio
  
Chr. number: 24
Strand: -1
Band:
Gene start: 26491904
Gene end: 26632182
  
Corresponding Affymetrix probe sets: Dr.17465.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000007356
Ensembl peptide - ENSDARP00000009975
Ensembl peptide - ENSDARP00000088564
Ensembl peptide - ENSDARP00000148380
swissprot - F1QAJ8
swissprot - F1QQG8
swissprot - Q32PQ9
ZFIN ID - ZDB-GENE-051113-320
Ensembl - ENSDARG00000009031
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TNIKENSGALG00000009298Gallus gallus
 TNIKENSG00000154310Homo sapiens
 TnikENSMUSG00000027692Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tnika / TRAF2 and NCK interacting kinase a / TNIK* / Q9UKE5* / P83510* / TRAF2 and NCK interacting kinase*ENSDARG0000005621885
map4k4 / mitogen-activated protein kinase kinase kinase kinase 4 / O95819*ENSDARG0000009867068
mink1 / misshapen-like kinase 1 / Q8N4C8* / Q9JM52* / misshapen-like kinase 1 (zebrafish)*ENSDARG0000003536067
si:zfos-2326c3.2 / NRK* / Q7Z2Y5* / Q9R0G8* / Nik related kinase* / Nik-related protein kinase *ENSDARG0000009868057
map4k3a / mitogen-activated protein kinase kinase kinase kinase 3a / Q99JP0* / MAP4K3* / Q8IVH8* / mitogen-activated protein kinase kinase kinase kinase 3*ENSDARG0000008774217
map4k3b / mitogen-activated protein kinase kinase kinase kinase 3bENSDARG0000007135716
map4k5 / mitogen-activated protein kinase kinase kinase kinase 5 / Q8BPM2*ENSDARG0000003912516
map4k6 / mitogen-activated protein kinase kinase kinase kinase 6 / Q61161* / MAP4K2* / Q12851* / mitogen-activated protein kinase kinase kinase kinase 2*ENSDARG0000003344414
map4k2 / mitogen-activated protein kinase kinase kinase kinase 2 / Q12851* / Q61161*ENSDARG0000000123414
slkb / STE20-like kinase bENSDARG000000125749
stk10 / serine/threonine kinase 10 / O94804*ENSDARG000001018948
slka / STE20-like kinase a / SLK* / Q9H2G2* / O54988* / STE20 like kinase* / STE20-like serine/threonine-protein kinase *ENSDARG000000615258
si:dkey-81j8.6ENSDARG000000888317
CABZ01099833.1 / P70218* / MAP4K1* / Q92918* / mitogen-activated protein kinase kinase kinase kinase 1* / Mus musculus mitogen-activated protein kinase kinase kinase kinase 1 (Map4k1), tran...ENSDARG000001140262


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001180  Citron homology (CNH) domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0000185 activation of MAPKKK activity IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0048812 neuron projection morphogenesis IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008349 MAP kinase kinase kinase kinase activity IBA
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
Oxidative Stress Induced Senescence


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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