ENSDARG00000061525


Danio rerio

Features
Gene ID: ENSDARG00000061525
  
Biological name :slka
  
Synonyms : slka / STE20-like kinase a
  
Possible biological names infered from orthology : O54988 / Q9H2G2 / SLK / STE20 like kinase / STE20-like serine/threonine-protein kinase
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 24781188
Gene end: 24826607
  
Corresponding Affymetrix probe sets: Dr.26369.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000115744
Ensembl peptide - ENSDARP00000155211
Ensembl peptide - ENSDARP00000082219
Ensembl peptide - ENSDARP00000113992
NCBI entrez gene - 568838     See in Manteia.
RefSeq - NM_001145601
RefSeq Peptide - NP_001139073
swissprot - B7ZD09
swissprot - F1Q5H3
swissprot - F1Q6R1
ZFIN ID - ZDB-GENE-050411-66
Ensembl - ENSDARG00000061525
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLKENSGALG00000008318Gallus gallus
 SLKENSG00000065613Homo sapiens
 SlkENSMUSG00000025060Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
slkb / STE20-like kinase bENSDARG0000001257459
stk10 / serine/threonine kinase 10 / O94804*ENSDARG0000010189437
si:dkey-81j8.6ENSDARG0000008883133
mink1 / misshapen-like kinase 1 / Q8N4C8* / Q9JM52* / misshapen-like kinase 1 (zebrafish)*ENSDARG0000003536017
tnika / TRAF2 and NCK interacting kinase a / TNIK* / Q9UKE5* / P83510* / TRAF2 and NCK interacting kinase*ENSDARG0000005621817
map4k3b / mitogen-activated protein kinase kinase kinase kinase 3bENSDARG0000007135716
map4k5 / mitogen-activated protein kinase kinase kinase kinase 5 / Q8BPM2*ENSDARG0000003912515
map4k3a / mitogen-activated protein kinase kinase kinase kinase 3a / Q99JP0* / MAP4K3* / Q8IVH8* / mitogen-activated protein kinase kinase kinase kinase 3*ENSDARG0000008774215
si:zfos-2326c3.2 / NRK* / Q7Z2Y5* / Q9R0G8* / Nik related kinase* / Nik-related protein kinase *ENSDARG0000009868015
map4k4 / mitogen-activated protein kinase kinase kinase kinase 4 / O95819*ENSDARG0000009867015
map4k2 / mitogen-activated protein kinase kinase kinase kinase 2 / Q12851* / Q61161*ENSDARG0000000123414
map4k6 / mitogen-activated protein kinase kinase kinase kinase 6 / Q61161* / MAP4K2* / Q12851* / mitogen-activated protein kinase kinase kinase kinase 2*ENSDARG0000003344414
CABZ01099833.1 / P70218* / MAP4K1* / Q92918* / mitogen-activated protein kinase kinase kinase kinase 1* / Mus musculus mitogen-activated protein kinase kinase kinase kinase 1 (Map4k1), tran...ENSDARG0000011402610
tnikb / TRAF2 and NCK interacting kinase b / TNIK* / Q9UKE5* / P83510* / TRAF2 and NCK interacting kinase*ENSDARG000000090313


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR022165  Polo kinase kinase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0023014 signal transduction by protein phosphorylation IBA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0032147 activation of protein kinase activity IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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