Manteia

ENSDARG00000039125

Danio rerio

Features

Gene ID:	ENSDARG00000039125

Biological name :	map4k5

Synonyms :	map4k5 / mitogen-activated protein kinase kinase kinase kinase 5

Possible biological names infered from orthology :	Q8BPM2

Species:	Danio rerio

Chr. number:	13
Strand:	-1
Band:
Gene start:	36705595
Gene end:	36761454

Corresponding Affymetrix probe sets:	Dr.4000.1.S1_at (Zebrafish Array) NM_199913_at (Zebrafish Genome Array with custom cdf files)

Cross references:	Ensembl peptide - ENSDARP00000034684 Ensembl peptide - ENSDARP00000119514 NCBI entrez gene - 334565 See in Manteia. RefSeq - NM_199913 RefSeq - XM_005156977 RefSeq - XM_009307462 RefSeq Peptide - NP_956207 swissprot - B8A6H0 swissprot - B8A6G9 ZFIN ID - ZDB-GENE-030131-6497 Ensembl - ENSDARG00000039125

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
MAP4K5	ENSGALG00000012321	Gallus gallus
MAP4K5	ENSG00000012983	Homo sapiens
Map4k5	ENSMUSG00000034761	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
map4k3a / mitogen-activated protein kinase kinase kinase kinase 3a / Q99JP0* / MAP4K3* / Q8IVH8* / mitogen-activated protein kinase kinase kinase kinase 3*	ENSDARG00000087742	64
map4k3b / mitogen-activated protein kinase kinase kinase kinase 3b	ENSDARG00000071357	63
map4k6 / mitogen-activated protein kinase kinase kinase kinase 6 / Q61161* / MAP4K2* / Q12851* / mitogen-activated protein kinase kinase kinase kinase 2*	ENSDARG00000033444	50
map4k2 / mitogen-activated protein kinase kinase kinase kinase 2 / Q12851* / Q61161*	ENSDARG00000001234	50
mink1 / misshapen-like kinase 1 / Q8N4C8* / Q9JM52* / misshapen-like kinase 1 (zebrafish)*	ENSDARG00000035360	29
tnika / TRAF2 and NCK interacting kinase a / TNIK* / Q9UKE5* / P83510* / TRAF2 and NCK interacting kinase*	ENSDARG00000056218	28
si:zfos-2326c3.2 / NRK* / Q7Z2Y5* / Q9R0G8* / Nik related kinase* / Nik-related protein kinase *	ENSDARG00000098680	26
map4k4 / mitogen-activated protein kinase kinase kinase kinase 4 / O95819*	ENSDARG00000098670	26
CABZ01099833.1 / P70218* / MAP4K1* / Q92918* / mitogen-activated protein kinase kinase kinase kinase 1* / Mus musculus mitogen-activated protein kinase kinase kinase kinase 1 (Map4k1), tran...	ENSDARG00000114026	26
slka / STE20-like kinase a / SLK* / Q9H2G2* / O54988* / STE20 like kinase* / STE20-like serine/threonine-protein kinase *	ENSDARG00000061525	21
slkb / STE20-like kinase b	ENSDARG00000012574	20
si:dkey-81j8.6	ENSDARG00000088831	17
stk10 / serine/threonine kinase 10 / O94804*	ENSDARG00000101894	15
tnikb / TRAF2 and NCK interacting kinase b / TNIK* / Q9UKE5* / P83510* / TRAF2 and NCK interacting kinase*	ENSDARG00000009031	10

Protein motifs (from Interpro)

Interpro ID	Name
IPR000719	Protein kinase domain
IPR001180	Citron homology (CNH) domain
IPR011009	Protein kinase-like domain superfamily
IPR017441	Protein kinase, ATP binding site
IPR021160	Mitogen-activated protein (MAP) kinase kinase kinase kinase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000165	MAPK cascade	IEA
biological_process	GO:0000185	activation of MAPKKK activity	IEA
biological_process	GO:0006468	protein phosphorylation	IEA
biological_process	GO:0007346	regulation of mitotic cell cycle	IBA
biological_process	GO:0016310	phosphorylation	IEA
biological_process	GO:0031098	stress-activated protein kinase signaling cascade	IBA
biological_process	GO:0042981	regulation of apoptotic process	IBA
cellular_component	GO:0005737	cytoplasm	IBA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0004672	protein kinase activity	IEA
molecular_function	GO:0004674	protein serine/threonine kinase activity	IEA
molecular_function	GO:0005524	ATP binding	IEA
molecular_function	GO:0008349	MAP kinase kinase kinase kinase activity	IEA
molecular_function	GO:0016301	kinase activity	IEA
molecular_function	GO:0016740	transferase activity	IEA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr