ENSDARG00000056218


Danio rerio

Features
Gene ID: ENSDARG00000056218
  
Biological name :tnika
  
Synonyms : tnika / TRAF2 and NCK interacting kinase a
  
Possible biological names infered from orthology : P83510 / Q9UKE5 / TNIK / TRAF2 and NCK interacting kinase
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 25657958
Gene end: 25817227
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000051233
Ensembl peptide - ENSDARP00000133707
NCBI entrez gene - 325042     See in Manteia.
swissprot - A0A0R4IEP9
swissprot - B0UY93
ZFIN ID - ZDB-GENE-030131-3767
Ensembl - ENSDARG00000056218
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TNIKENSGALG00000009298Gallus gallus
 TNIKENSG00000154310Homo sapiens
 TnikENSMUSG00000027692Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mink1 / misshapen-like kinase 1 / Q8N4C8* / Q9JM52* / misshapen-like kinase 1 (zebrafish)*ENSDARG0000003536065
map4k4 / mitogen-activated protein kinase kinase kinase kinase 4 / O95819*ENSDARG0000009867055
si:zfos-2326c3.2 / NRK* / Q7Z2Y5* / Q9R0G8* / Nik related kinase* / Nik-related protein kinase *ENSDARG0000009868048
tnikb / TRAF2 and NCK interacting kinase b / TNIK* / Q9UKE5* / P83510* / TRAF2 and NCK interacting kinase*ENSDARG0000000903135
map4k3a / mitogen-activated protein kinase kinase kinase kinase 3a / Q99JP0* / MAP4K3* / Q8IVH8* / mitogen-activated protein kinase kinase kinase kinase 3*ENSDARG0000008774220
map4k3b / mitogen-activated protein kinase kinase kinase kinase 3bENSDARG0000007135720
map4k5 / mitogen-activated protein kinase kinase kinase kinase 5 / Q8BPM2*ENSDARG0000003912519
map4k6 / mitogen-activated protein kinase kinase kinase kinase 6 / Q61161* / MAP4K2* / Q12851* / mitogen-activated protein kinase kinase kinase kinase 2*ENSDARG0000003344417
map4k2 / mitogen-activated protein kinase kinase kinase kinase 2 / Q12851* / Q61161*ENSDARG0000000123417
slka / STE20-like kinase a / SLK* / Q9H2G2* / O54988* / STE20 like kinase* / STE20-like serine/threonine-protein kinase *ENSDARG0000006152516
slkb / STE20-like kinase bENSDARG0000001257415
si:dkey-81j8.6ENSDARG0000008883112
stk10 / serine/threonine kinase 10 / O94804*ENSDARG0000010189412
CABZ01099833.1 / P70218* / MAP4K1* / Q92918* / mitogen-activated protein kinase kinase kinase kinase 1* / Mus musculus mitogen-activated protein kinase kinase kinase kinase 1 (Map4k1), tran...ENSDARG0000011402611


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001180  Citron homology (CNH) domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0000185 activation of MAPKKK activity IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0007369 gastrulation IMP
 biological_processGO:0008360 regulation of cell shape IMP
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0048812 neuron projection morphogenesis IBA
 biological_processGO:0060027 convergent extension involved in gastrulation IMP
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008349 MAP kinase kinase kinase kinase activity IBA


Pathways (from Reactome)
Pathway description
Oxidative Stress Induced Senescence


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000086 EVL EVL cell shape , abnormal
EVL structure , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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