ENSG00000012983


Homo sapiens

Features
Gene ID: ENSG00000012983
  
Biological name :MAP4K5
  
Synonyms : MAP4K5 / mitogen-activated protein kinase kinase kinase kinase 5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q22.1
Gene start: 50418501
Gene end: 50561126
  
Corresponding Affymetrix probe sets: 203552_at (Human Genome U133 Plus 2.0 Array)   203553_s_at (Human Genome U133 Plus 2.0 Array)   211081_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000013125
Ensembl peptide - ENSP00000451926
Ensembl peptide - ENSP00000451980
Ensembl peptide - ENSP00000452289
Ensembl peptide - ENSP00000451452
NCBI entrez gene - 11183     See in Manteia.
OMIM - 604923
RefSeq - XM_011536379
RefSeq - NM_006575
RefSeq - NM_198794
RefSeq - XM_006720013
RefSeq - XM_011536377
RefSeq - XM_011536378
RefSeq Peptide - NP_006566
RefSeq Peptide - NP_942089
swissprot - A0A0A0MQR1
swissprot - G3V4T8
swissprot - G3V5C6
swissprot - G3V4Q4
swissprot - G3V3V7
Ensembl - ENSG00000012983
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 map4k5ENSDARG00000039125Danio rerio
 MAP4K5ENSGALG00000012321Gallus gallus
 Map4k5ENSMUSG00000034761Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAP4K3 / Q8IVH8 / mitogen-activated protein kinase kinase kinase kinase 3ENSG0000001156670
MAP4K2 / Q12851 / mitogen-activated protein kinase kinase kinase kinase 2ENSG0000016806751
MAP4K1 / Q92918 / mitogen-activated protein kinase kinase kinase kinase 1ENSG0000010481444
MAP4K4 / O95819 / mitogen-activated protein kinase kinase kinase kinase 4ENSG0000007105431
MINK1 / Q8N4C8 / misshapen like kinase 1ENSG0000014150331
TNIK / Q9UKE5 / TRAF2 and NCK interacting kinaseENSG0000015431030
NRK / Q7Z2Y5 / Nik related kinaseENSG0000012357224
SLK / Q9H2G2 / STE20 like kinaseENSG0000006561322
STK10 / O94804 / serine/threonine kinase 10ENSG0000007278621


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001180  Citron homology (CNH) domain
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR021160  Mitogen-activated protein (MAP) kinase kinase kinase kinase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008349 MAP kinase kinase kinase kinase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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