ENSGALG00000017199


Gallus gallus

Features
Gene ID: ENSGALG00000017199
  
Biological name :MAML2
  
Synonyms : MAML2 / mastermind like transcriptional coactivator 2
  
Possible biological names infered from orthology : mastermind-like protein 2 isoform 1 / Q8IZL2
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 184996598
Gene end: 185204663
  
Corresponding Affymetrix probe sets: GgaAffx.11034.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000027746
NCBI entrez gene - 428088     See in Manteia.
RefSeq - XM_015280608
swissprot - F1NYN6
Ensembl - ENSGALG00000017199
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01061591.1ENSDARG00000112977Danio rerio
 MAML2ENSG00000184384Homo sapiens
 Maml2ENSMUSG00000031925Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAML3 / mastermind like transcriptional coactivator 3 / Q96JK9*ENSGALG0000000980926
MAML1 / mastermind like transcriptional coactivator 1 / Q6T264* / Q92585* / Mastermind-like protein 1 *ENSGALG0000000592920


Protein motifs (from Interpro)
Interpro ID Name
 IPR019082  Neurogenic mastermind-like, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007221 positive regulation of transcription of Notch receptor target IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0003713 transcription coactivator activity IBA


Pathways (from Reactome)
Pathway description
NOTCH2 intracellular domain regulates transcription
RUNX3 regulates NOTCH signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002922 NOTCH2 / Q04721*  / reaction / complex






 

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contact: otassy@igbmc.fr