ENSMUSG00000031925


Mus musculus

Features
Gene ID: ENSMUSG00000031925
  
Biological name :Maml2
  
Synonyms : Maml2 / mastermind-like protein 2 isoform 1
  
Possible biological names infered from orthology : mastermind like transcriptional coactivator 2 / Q8IZL2
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: A1
Gene start: 13297957
Gene end: 13709388
  
Corresponding Affymetrix probe sets: 10583207 (MoGene1.0st)   10598101 (MoGene1.0st)   1427926_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000124083
Ensembl peptide - ENSMUSP00000034401
Ensembl peptide - ENSMUSP00000136866
NCBI entrez gene - 270118     See in Manteia.
MGI - MGI:2389460
RefSeq - NM_001013813
RefSeq - NM_173776
RefSeq Peptide - NP_776137
RefSeq Peptide - NP_001013835
swissprot - E9Q7L5
swissprot - F6U238
Ensembl - ENSMUSG00000031925
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01061591.1ENSDARG00000112977Danio rerio
 MAML2ENSGALG00000017199Gallus gallus
 MAML2ENSG00000184384Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Maml1 / Q6T264 / Mastermind-like protein 1 / Q92585* / mastermind like transcriptional coactivator 1*ENSMUSG0000005056723
Maml3 / mastermind like transcriptional coactivator 3 / Q96JK9*ENSMUSG0000006114323


Protein motifs (from Interpro)
Interpro ID Name
 IPR019082  Neurogenic mastermind-like, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007221 positive regulation of transcription of Notch receptor target IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISA
 cellular_componentGO:0005634 nucleus ISA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0003713 transcription coactivator activity ISA


Pathways (from Reactome)
Pathway description
NOTCH1 Intracellular Domain Regulates Transcription
NOTCH2 intracellular domain regulates transcription
Notch-HLH transcription pathway
RUNX3 regulates NOTCH signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000039191 Rbpj / P31266 / Recombining binding protein suppressor of hairless / Q06330* / recombination signal binding protein for immunoglobulin kappa J region*  / complex / reaction
 ENSMUSG00000038146 Notch3 / Q61982 / Neurogenic locus notch homolog protein 3 Notch 3 extracellular truncation Notch 3 intracellular domain / Q9UM47*  / complex
 ENSMUSG00000027878 Notch2 / Q04721*  / reaction / complex






 

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