ENSGALG00000021275


Gallus gallus

Features
Gene ID: ENSGALG00000021275
  
Biological name :LTC4S
  
Synonyms : leukotriene C4 synthase / LTC4S
  
Possible biological names infered from orthology : Q16873 / Q60860
  
Species: Gallus gallus
  
Chr. number: 13
Strand: -1
Band:
Gene start: 13508916
Gene end: 13512923
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000033663
NCBI entrez gene - 770619     See in Manteia.
RefSeq - XM_001233957
RefSeq - XM_015293938
RefSeq - XM_015293936
RefSeq - XM_015293937
swissprot - E1BXH6
Ensembl - ENSGALG00000021275
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ltc4sENSDARG00000062598Danio rerio
 LTC4SENSG00000213316Homo sapiens
 Ltc4sENSMUSG00000020377Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000001145056
MGST2 / microsomal glutathione S-transferase 2 / Q99735*ENSGALG0000000980331
ALOX5AP / arachidonate 5-lipoxygenase activating protein / P20292* / P30355*ENSGALG0000002678126


Protein motifs (from Interpro)
Interpro ID Name
 IPR001129  Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein
 IPR001446  5-lipoxygenase-activating protein
 IPR023352  Membrane associated eicosanoid/glutathione metabolism-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006691 leukotriene metabolic process IEA
 biological_processGO:0019370 leukotriene biosynthetic process IBA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005635 nuclear envelope IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004364 glutathione transferase activity IBA
 molecular_functionGO:0004464 leukotriene-C4 synthase activity IEA
 molecular_functionGO:0004602 glutathione peroxidase activity IBA
 molecular_functionGO:0008047 enzyme activator activity IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of 5-eicosatetraenoic acids
Synthesis of Leukotrienes (LT) and Eoxins (EX)
Synthesis of Lipoxins (LX)
Biosynthesis of maresin conjugates in tissue regeneration (MCTR)
Biosynthesis of protectin and resolvin conjugates in tissue regeneration (PCTR and RCTR)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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