ENSDARG00000062598


Danio rerio

Features
Gene ID: ENSDARG00000062598
  
Biological name :ltc4s
  
Synonyms : leukotriene C4 synthase / ltc4s
  
Possible biological names infered from orthology : Q16873 / Q60860
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 16370063
Gene end: 16379843
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000085144
NCBI entrez gene - 100535432     See in Manteia.
swissprot - E7F8E5
ZFIN ID - ZDB-GENE-110411-32
Ensembl - ENSDARG00000062598
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000011450Gallus gallus
 LTC4SENSGALG00000021275Gallus gallus
 LTC4SENSG00000213316Homo sapiens
 Ltc4sENSMUSG00000020377Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mgst2 / microsomal glutathione S-transferase 2 / Q99735*ENSDARG0000007134538
alox5ap / arachidonate 5-lipoxygenase-activating protein / P20292* / P30355*ENSDARG0000005475526


Protein motifs (from Interpro)
Interpro ID Name
 IPR001129  Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein
 IPR001446  5-lipoxygenase-activating protein
 IPR023352  Membrane associated eicosanoid/glutathione metabolism-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006691 leukotriene metabolic process IEA
 biological_processGO:0019370 leukotriene biosynthetic process IBA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005635 nuclear envelope IBA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004364 glutathione transferase activity IBA
 molecular_functionGO:0004464 leukotriene-C4 synthase activity IBA
 molecular_functionGO:0004602 glutathione peroxidase activity IBA
 molecular_functionGO:0008047 enzyme activator activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of 5-eicosatetraenoic acids
Synthesis of Leukotrienes (LT) and Eoxins (EX)
Synthesis of Lipoxins (LX)
Biosynthesis of maresin conjugates in tissue regeneration (MCTR)
Biosynthesis of protectin and resolvin conjugates in tissue regeneration (PCTR and RCTR)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000054755 alox5ap / arachidonate 5-lipoxygenase-activating protein / P20292* / P30355*  / complex
 ENSDARG00000062598 ltc4s / leukotriene C4 synthase / Q16873* / Q60860*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr