ENSGALG00000023066


Gallus gallus

Features
Gene ID: ENSGALG00000023066
  
Biological name :DNAJA1
  
Synonyms : DNAJA1 / DnaJ heat shock protein family (Hsp40) member A1
  
Possible biological names infered from orthology : DnaJ homolog subfamily A member 1 / P31689 / P63037
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 70593750
Gene end: 70601481
  
Corresponding Affymetrix probe sets: Gga.5644.1.S1_s_at (Chicken Array)   Gga.5644.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000036774
Ensembl peptide - ENSGALP00000064370
Ensembl peptide - ENSGALP00000063123
NCBI entrez gene - 427376     See in Manteia.
RefSeq - NM_001012945
RefSeq Peptide - NP_001012963
swissprot - A0A1L1RZR2
swissprot - A0A1L1RWB6
swissprot - Q5ZJV3
Ensembl - ENSGALG00000023066
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnaja1ENSDARG00000030972Danio rerio
 DNAJA1ENSG00000086061Homo sapiens
 Dnaja1ENSMUSG00000028410Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DNAJA4 / DnaJ heat shock protein family (Hsp40) member A4 / Q8WW22* / Q9JMC3* / Mus musculus DnaJ heat shock protein family (Hsp40) member A4 (Dnaja4), transcript variant 1, mRNA.*ENSGALG0000003685072
ENSGALG0000003907262
DNAJA2 / DnaJ heat shock protein family (Hsp40) member A2 / O60884* / Q9QYJ0* / DnaJ homolog subfamily A member 2 *ENSGALG0000000411555
Q99KV1* / Q9UBS4* / DNAJB11* / AC068631.2* / DnaJ homolog subfamily B member 11 * / DnaJ heat shock protein family (Hsp40) member B11*ENSGALG0000000656432


Protein motifs (from Interpro)
Interpro ID Name
 IPR001305  Heat shock protein DnaJ, cysteine-rich domain
 IPR001623  DnaJ domain
 IPR002939  Chaperone DnaJ, C-terminal
 IPR008971  HSP40/DnaJ peptide-binding
 IPR012724  Chaperone DnaJ
 IPR018253  DnaJ domain, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0009408 response to heat IEA
 biological_processGO:0030317 flagellated sperm motility IEA
 biological_processGO:0030521 androgen receptor signaling pathway IEA
 biological_processGO:0031397 negative regulation of protein ubiquitination IEA
 biological_processGO:0032781 positive regulation of ATPase activity IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043508 negative regulation of JUN kinase activity IEA
 biological_processGO:0051223 regulation of protein transport IEA
 biological_processGO:0070585 protein localization to mitochondrion IEA
 biological_processGO:1901998 toxin transport IEA
 biological_processGO:1903748 negative regulation of establishment of protein localization to mitochondrion IEA
 biological_processGO:1905259 negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0000151 ubiquitin ligase complex IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0001664 G-protein coupled receptor binding IEA
 molecular_functionGO:0001671 ATPase activator activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0030544 Hsp70 protein binding IEA
 molecular_functionGO:0030957 Tat protein binding IEA
 molecular_functionGO:0031072 heat shock protein binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050750 low-density lipoprotein particle receptor binding IEA
 molecular_functionGO:0051082 unfolded protein binding IEA
 molecular_functionGO:0051087 chaperone binding IEA
 molecular_functionGO:0055131 C3HC4-type RING finger domain binding IEA


Pathways (from Reactome)
Pathway description
HSP90 chaperone cycle for steroid hormone receptors (SHR)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000010175 HSP90AB1 / heat shock cognate protein HSP 90-beta / P08238* / P11499* / Heat shock protein HSP 90-beta * / heat shock protein 90 alpha family class B member 1*  / reaction
 ENSGALG00000023066 DNAJA1 / DnaJ heat shock protein family (Hsp40) member A1 / P31689* / P63037* / DnaJ homolog subfamily A member 1 *  / complex






 

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